6 patents
Utility
ANTI-CD-25 Antibody
25 May 23
Materials and methods for using polypeptides containing fragments and variants of the antibody(ies) or portion(s) thereof that bind CD25 to treat cancer alone or in combination with other anti-neoplastic agents.
Dillon Phan, Martin Brenner, Brian Berquist, Peter Kipp, Tam Phuong, Kevin Babilonia, Tom Hsu, Lufei Hu, James Talmage Taylor, JR., Cory Schwartz
Filed: 22 Aug 22
Utility
Machine Learning Method for Protein Modelling to Design Engineered Peptides
30 Mar 23
Provided herein are methods for design of engineered polypeptides that recapitulate molecular structure features of a predetermined portion of a reference protein structure, e.g., an antibody epitope or a protein binding site.
Matthew P. Greving, Alexander T. Taguchi, Kevin E. Hauser
Filed: 7 Oct 22
Utility
Machine learning method for protein modelling to design engineered peptides
3 Jan 23
Provided herein are methods for design of engineered polypeptides that recapitulate molecular structure features of a predetermined portion of a reference protein structure, e.g., an antibody epitope or a protein binding site.
Matthew P. Greving, Alexander T. Taguchi, Kevin E. Hauser
Filed: 1 Dec 20
Utility
SARS-COV-2 Subunit and Variant Vaccines
24 Nov 22
The present invention includes an immunogenic protein, constructs, vectors, and methods of making, comprising at least 90% amino acid identity to at least one antigenic peptide selected from: a coronavirus Receptor Binding Domain (RBD), coronavirus a Receptor Binding Motif (RBM) of a coronavirus spike protein, a coronavirus spike protein N-terminus, a nucleocapsid protein, one or more T cell epitopes from a coronavirus spike protein, or one or more T cell epitopes from a coronavirus nucleocapsid protein, or combination thereof.
Peter Kipp, Brian Berquist, Sreenath Palle
Filed: 21 Apr 22
Utility
LICHENASE-COVID-19 Based Vaccine
16 Sep 21
The present invention includes an immunogenic protein, nucleic acid, plant and immunization comprising a fusion protein that has at least 90% amino acid identity to an amino acid sequence of a modified thermostable lichenase (LicKM) polypeptide as set forth in SEQ ID NO:9, wherein the LicKM polypeptide comprises an N-terminus, a C-terminus, and an inner loop region, and wherein a Receptor Binding Domain (RBD) or a Receptor Binding Motif (RBM) of a coronavirus spike protein is positioned at, at least one of, the N-terminus, the C-terminus, or in a loop region of the LicKM polypeptide.
Sylvain Marcel
Filed: 11 Mar 21
Utility
Materials and methods for producing endostatin fusion polypeptides in plant cells
23 Nov 20
This document provides materials and methods for producing endostatin fusion polypeptides having anti-fibrotic activity.
Carol Feghali-Bostwick, Terence E Ryan, Hal S. Padgett, Matthew McGee
Filed: 2 Jun 16
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