52 patents
Page 2 of 3
Utility
Compositions comprising methylphenidate-prodrugs, processes of making and using the same
23 Mar 21
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 18 Feb 20
Utility
Therapeutic formulation for reduced drug side effects
9 Feb 21
The present invention provides drug therapy formulations for reducing the side effects associated with a therapeutic.
Subhash Desai
Filed: 23 Sep 19
Utility
Levorphanol Prodrugs and Processes for Making and Using Them
6 Jan 21
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and vitamin compounds chemically conjugated to levorphanol ((−)-17-methylmorphinan-3-ol) to form novel prodrugs and compositions of levorphanol.
Travis Mickle, Sven Guenther, Sanjib Bera
Filed: 11 Apr 18
Utility
Pharmaceutically acceptable salts and polymorphic forms of hydrocodone benzoic acid enol ester and processes for making same
21 Dec 20
Compositions comprising hydrocodone benzoic acid enol ester to form novel prodrugs including hydrocodone benzoic acid enol ester salts, and various polymorphs.
Travis Mickle, Sven Guenther, Christal Mickle, Guochen Chi, Jaroslaw Kanski, Andrea K. Martin, Bindu Bera
Filed: 17 Mar 19
Utility
Dextrorphan Prodrugs and Processes for Making and Using Them
16 Dec 20
The presently described technology provides compositions of one or more of oxoacids, polyethylene glycols, and/or vitamin compounds chemically conjugated to dextrorphan, (+)-17-methylmorphinan-3-ol), to form novel prodrugs and compositions of dextrorphan.
Travis Mickle, Sven Guenther, Sanjib Bera
Filed: 11 Apr 18
Utility
Levorphanol Prodrugs and Processes for Making and Using Them
16 Dec 20
The presently described technology provides compositions of one or more of oxoacids, amino acids, polyethylene glycols, and/or vitamin compounds chemically conjugated to levorphanol ((−)-17-methylmorphinan-3-ol) to form novel prodrugs and compositions of levorphanol.
Travis Mickle, Sven Guenther, Sanjib Bera
Filed: 11 Apr 18
Utility
Compositions comprising methylphenidate-prodrugs, processes of making and using the same
7 Dec 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 17 Feb 20
Utility
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
30 Nov 20
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal.
Travis Mickle, Sven Guenther, Christal Mickle, Guochen Chi, Jaroslaw Kanski, Andrea K. Martin, Bindu Bera
Filed: 21 Oct 18
Utility
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxymorphone, prodrugs, methods of making and use thereof
31 Aug 20
The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-α-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone.
Travis Mickle, Sven Guenther, Sanjib Bera, Jaroslaw Kanski, Andrea Martin
Filed: 16 Sep 19
Utility
Methylphenidate-prodrugs, processes of making and using the same
31 Aug 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 3 Jun 19
Utility
Serdexmethylphenidate Conjugates, Compositions And Methods Of Use Thereof
29 Jul 20
The present technology is directed to one or more compositions comprising serdexmethylphenidate conjugates and unconjugated d-methylphenidate and/or a pharmaceutically acceptable salt thereof.
Sven Guenther, Guochen Chi, Travis Mickle
Filed: 26 Feb 20
Utility
Compositions Comprising Methylphenidate-prodrugs, Processes of Making and Using the Same
10 Jun 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 17 Feb 20
Utility
Compositions Comprising Methylphenidate-prodrugs, Processes of Making and Using the Same
10 Jun 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 17 Feb 20
Utility
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
18 May 20
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal.
Travis Mickle, Sven Guenther, Christal Mickle, Guochen Chi, Jaroslaw Kanski, Andrea K. Martin, Bindu Bera
Filed: 20 Feb 18
Utility
D-amphetamine Compounds, Compositions, and Processes for Making and Using the Same
29 Apr 20
Disclosed are d-amphetamine compounds and compositions comprising at least one organic acid covalently bound to d-amphetamine, a salt thereof, a derivative thereof, or a combination thereof.
Sven Guenther, Guochen Chi, Travis Mickle
Filed: 28 Oct 19
Utility
D-amphetamine Compounds, Compositions, and Processes for Making and Using the Same
29 Apr 20
Sven Guenther, Guochen Chi, Travis Mickle
Filed: 28 Oct 19
Utility
Methylphenidate-prodrugs, processes of making and using the same
9 Mar 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 3 Jun 19
Utility
Methylphenidate-prodrugs, processes of making and using the same
9 Mar 20
The present technology is directed to compositions comprising d-threo-methylphenidate conjugates and unconjugated methylphenidate.
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 3 Jun 19
Utility
Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof
2 Mar 20
The presently described technology provides methods of treating a patient having moderate to severe pain, narcotic or opioid abuse or narcotic or opioid withdrawal.
Travis Mickle, Sven Guenther, Christal Mickle, Guochen Chi, Jaroslaw Kanski, Andrea K. Martin, Bindu Bera
Filed: 14 Dec 17
Utility
Compositions Comprising Methlphenidate-prodrugs, Processes of Making and Using the Same
26 Feb 20
Travis Mickle, Sven Guenther, Guochen Chi
Filed: 29 Sep 19