23 patents
Page 2 of 2
Utility
Proteostasis regulators
13 Jan 20
The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
Megan Foley, Bradley Tait, Matthew Cullen
Filed: 9 Jan 17
Utility
Compounds, Compositions, and Methods for Increasing CFTR Activity
8 Jan 20
The present disclosure is directed to disclosed compounds that increase cystic fibrosis transmembrane conductance regulator (CFTR) activity as measured in human bronchial epithelial (hBE) cells.
Daniel Parks, Cecilia M. Bastos, Matthew Cullen, Benito Munoz
Filed: 20 Jun 17
Utility
Compounds, Compositions, and Methods for Increasing CFTR Activity
9 Oct 19
The present disclosure features disclosed compounds which can increase cystic fibrosis transmembrane conductance regulator (CFTR) activity as measured in human bronchial epithelial (hBE) cells.
Cecilia M. Bastos, Benito Munoz, Bradley Tait
Filed: 13 Nov 18