42 patents
Page 3 of 3
Utility
Tolerogenic synthetic nanocarriers for generating CD8+ regulatory T cells
14 Oct 19
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering MHC Class I-restricted and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to generate tolerogenic immune responses against the antigen, such as the generation of antigen-specific CD8+ regulatory T cells.
Takashi Kei Kishimoto, Christopher Fraser, Roberto A. Maldonado
Filed: 26 Jul 15
Utility
Methods related to administering immunosuppressants and therapeutic macromolecules at a reduced pharmacodynamically effective dose
7 Oct 19
Disclosed are compositions and methods that provide pharmacodynamic effects specific to therapeutic macromolecules.
Roberto A. Maldonado, Takashi Kei Kishimoto
Filed: 1 May 14