Docoh
Loading...

ADPT Adaptive Biotechnologies

APP
Utility
Methods of Monitoring Conditions by Sequence Analysis
7 Oct 21
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer.
Malek Faham, Thomas Willis
Filed: 16 Apr 21
GRANT
Utility
Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing
20 Jul 21
Methods of monitoring and measuring dynamic adaptive immune cell responses are provided.
Harlan S. Robins, William Sumner DeWitt, III, Ryan O. Emerson
Filed: 24 Nov 15
GRANT
Utility
Methods for diagnosing infectious disease and determining HLA status using immune repertoire sequencing
29 Jun 21
Methods are provided for predicting a subject's infection status using high-throughput T cell receptor sequencing to match the subject's TCR repertoire to a known set of disease-associated T cell receptor sequences.
Ryan O. Emerson, Harlan S. Robins, Mark Rieder, William Dewitt, III, Christopher Carlson
Filed: 24 Feb 16
GRANT
Utility
Method of identifying human compatible T cell receptors specific for an antigenic target
22 Jun 21
Methods are provided for identifying T cell receptors that specifically bind a particular antigenic target and can be used as therapeutics against disease.
Harlan S. Robins, Aude Georgiana Chapuis, Thomas M. Schmitt, Philip Greenberg, Anna Sherwood
Filed: 1 Apr 16
GRANT
Utility
High affinity T cell receptors and uses thereof
8 Jun 21
The present disclosure provides TCRs with high or enhanced affinity against various tumor associated antigens (including human Wilms tumor protein 1 (WT 1) epitopes and mesothelin epitopes), T cells expressing such high affinity antigen specific TCRs, nucleic acids encoding the same, and compositions for use in treating diseases or disorders in which cells overexpress one or more of these antigens, such as in cancer.
Thomas M. Schmitt, Philip D. Greenberg, Aude G. Chapuis, Harlan S. Robins, Anna M. Sherwood
Filed: 23 Dec 16
GRANT
Utility
Monitoring health and disease status using clonotype profiles
1 Jun 21
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias.
Malek Faham, Thomas Willis
Filed: 13 Dec 18
GRANT
Utility
Methods of monitoring conditions by sequence analysis
11 May 21
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer.
Malek Faham, Thomas Willis
Filed: 17 Dec 18
APP
Utility
Synthetic Strands For Nucleic Acid Sequencing And Related Methods And Systems
6 May 21
Provided are synthetic strands for nucleic acid sequencing.
Harlan S. Robins
Filed: 5 Nov 20
GRANT
Utility
Compositions and methods for measuring and calibrating amplification bias in multiplexed PCR reactions
19 Jan 21
Compositions and methods are described for standardizing the DNA amplification efficiencies of a highly heterogeneous set of oligonucleotide primers as may typically be used to amplify a heterogeneous set of DNA templates that contains rearranged lymphoid cell DNA encoding T cell receptors (TCR) or immunoglobulins (IG).
Harlan Saul Robins, Christopher Scott Carlson, Robert J. Livingston, Ryan O. Emerson, Anna M. Sherwood
Filed: 8 Jan 19
GRANT
Utility
Monitoring health and disease status using clonotype profiles
14 Dec 20
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias.
Malek Faham, Thomas Willis
Filed: 4 Sep 18
APP
Utility
Methods Using Randomer-Containing Synthetic Molecules
14 Oct 20
Methods are provided for correction of amplification bias and quantitation of adaptive immune cells in a sample using synthetic templates that include random oligonucleotide sequences.
Anna M. SHERWOOD, Ryan O. EMERSON, Harlan S. ROBINS, Mark J. RIEDER, Joe PARSONS
Filed: 30 Apr 20
GRANT
Utility
Monitoring health and disease status using clonotype profiles
31 Aug 20
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias.
Malek Faham, Thomas Willis
Filed: 29 Nov 17
GRANT
Utility
Method for genotyping clonotype profiles using sequence tags
6 Jan 20
The invention is directed to sequence-based profiling of populations of nucleic acids by multiplex amplification and attachment of one or more sequence tags to target nucleic acids and/or copies thereof followed by high-throughput sequencing of the amplification product.
Thomas Asbury, Kieran Hervold, Chitra Kotwaliwale, Malek Faham, Martin Moorhead, Li Weng, Tobias Wittkop, Jianbiao Zheng
Filed: 1 Aug 18
GRANT
Utility
Monitoring health and disease status using clonotype profiles
30 Dec 19
There is a need for improved methods for determining the diagnosis and prognosis of patients with conditions, including autoimmune disease and cancer, especially lymphoid neoplasms, such as lymphomas and leukemias.
Malek Faham, Thomas Willis
Filed: 8 Jun 17
GRANT
Utility
Determining antigen-specific T-cells
7 Oct 19
The invention is directed to methods for determining antigen-specific T cells.
Mark Klinger, Malek Faham
Filed: 29 Nov 17
GRANT
Utility
Identification of antigen-specific B cell receptors
30 Sep 19
Compositions and methods are disclosed for identifying B-cell receptor sequences that bind to corresponding antigens.
Mark Klinger
Filed: 19 Sep 17
  • 1
Patents are sorted by USPTO publication date, most recent first