43 patents
Utility
Dosing regimens and related compositions and methods
19 Dec 23
In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs.
Federico Grossi, Pascal Deschatelets, Cedric Francois, Patrick Johnson, Carolina Vega
Filed: 29 Apr 21
Utility
Methods of Treating Eye Disorders
30 Nov 23
Methods of treating eye disorders, e.g., age related macular degeneration, using C3 inhibitor, are disclosed.
Ravikanth Metlapally, Ramiro Magalhaes Ribeiro
Filed: 21 Sep 21
Utility
Rnas for Complement Inhibition
28 Sep 23
RNAs, such as miRNA and siRNA, and their use in treating complement-mediated disorders, are described.
Christian Mueller, Lukas Scheibler
Filed: 12 Sep 22
Utility
Methods of treating chronic disorders with complement inhibitors
1 Aug 23
In some aspects, the invention provides methods of treating a subject in need of treatment for a chronic complement-mediated disorder.
Cedric Francois, Pascal Deschatelets
Filed: 20 Apr 21
Utility
Cell-reactive, long-acting, or targeted compstatin analogs and uses thereof
30 May 23
In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs.
Cedric Francois, Pascal Deschatelets
Filed: 17 Mar 21
Utility
Rnas for Complement Inhibition
30 Mar 23
RNAs, such as miRNA and siRNA, and their use in treating complement-mediated disorders, are described.
Markus Hoßbach, Kathrin Hultsch
Filed: 13 Feb 21
Utility
Cell-reactive, Long-acting, or Targeted Compstatin Analogs and Related Compositions and Methods
23 Mar 23
In some aspects, the present invention provides cell-reactive compstatin analogs and compositions comprising cell-reactive compstatin analogs.
Cedric Francois, Pascal Deschatelets
Filed: 16 Feb 22
Utility
Apparatus and Methods for Assisting Breathing
9 Mar 23
The present invention provides, among other things, apparatus and methods of use for treating a subject in need of assistance with breathing.
Cedric Francois, Angus McLachlan
Filed: 11 Nov 22
Utility
Cell-penetrating Compstatin Analogs and Uses Thereof
9 Mar 23
In some aspects, the present invention cell-penetrating compstatin analog and compositions comprising cell-penetrating compstatin analog.
Cedric Francois, Pascal Deschatelets, Monica Gerber
Filed: 29 Jun 22
Utility
Treatment of Paroxysmal Nocturnal Hemoglobinuria
9 Mar 23
Methods and compositions for treatment of paroxysmal nocturnal hemoglobinuria are described.
Pascal Deschatelets, Cedric Francois, Federico Grossi, Sharon Morriss, Elizabeth F. Tan
Filed: 7 Jan 21
Utility
Combination Therapy for C3 Inhibition
12 Jan 23
In some aspects, the present invention provides certain combination therapies comprising compstatin analogs.
Cedric Francois
Filed: 12 Apr 22
Utility
Apparatus and methods for assisting breathing
20 Dec 22
The present invention provides, among other things, apparatus and methods of use for treating a subject in need of assistance with breathing.
Cedric Francois, Angus McLachlan
Filed: 3 Jun 20
Utility
RNAs for complement inhibition
29 Nov 22
RNAs, such as miRNA and siRNA, and their use in treating complement-mediated disorders, are described.
Christian Mueller, Lukas Scheibler
Filed: 20 Apr 20
Utility
Complement Inhibitor Dosing Regimens
8 Sep 22
Methods and compositions for inhibiting complement are described.
Pascal Deschatelets, Cedric Francois, Federico Grossi, Patrick Johnson, Lukas Scheibler
Filed: 17 Jul 20
Utility
Viral Vector Therapy
11 Aug 22
Methods and compositions for combined therapy with viral vectors and complement inhibitors are described.
Cedric Francois, Lukas Scheibler
Filed: 2 Jul 20
Utility
Methods and Compositions for Cancer Treatment and Treatment Selection
11 Aug 22
In some aspects, the disclosure provides methods of treating cancer or an infection.
Cedric Francois
Filed: 21 Sep 21
Utility
Cell-penetrating compstatin analogs and uses thereof
9 Aug 22
In some aspects, the present invention cell-penetrating compstatin analog and compositions comprising cell-penetrating compstatin analog.
Cedric Francois, Pascal Deschatelets, Monica Gerber
Filed: 18 Dec 20
Utility
Combination therapy for C3 inhibition
24 May 22
In some aspects, the present invention provides certain combination therapies comprising compstatin analogs.
Cedric Francois
Filed: 16 Oct 17
Utility
Detection of high risk drusen
5 Apr 22
In some aspects, methods of detecting complement activation in vivo, e.g., in an eye, are provided.
Cedric Francois, Pascal Deschatelets
Filed: 3 Apr 20
Utility
Cell-reactive, long-acting, or targeted compstatin analogs and related compositions and methods
5 Apr 22
In some aspects, the present invention provides compositions and methods (e.g. methods of treating, preventing, making, etc.) comprising compstatin analogs.
Cedric Francois, Pascal Deschatelets
Filed: 25 Jun 20