17 patents
Utility
NMR methods and systems for the rapid detection of bacteria
6 Dec 22
The invention features methods panels, cartridges, and systems for detecting pathogens and for diagnosing and treating diseases, including bacteremia and sepsis.
Ulrich Hans Thomann, Lori Anne Neely, Heidi Susanne Giese, Jessica Ann Townsend, Rahul Krishan Dhanda, Thomas Jay Lowery, Jr., Urvi Ved, Brendan Manning, Nu Ai Phung, Joanne Lawton Garver, Benjamin B. Stone
Filed: 20 Jan 17
Utility
Methods and Compositions for High Sensitivity Detection of Drug Resistance Markers
1 Dec 22
Provided herein are methods of amplifying and detecting drug resistance markers (e.g., antibiotic resistance genes) from pathogens in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).
Jessica Lee SNYDER, Brendan John MANNING, Daniel GAMERO, Heidi Susanne GIESE, Thomas J. LOWERY, Jr.
Filed: 4 Oct 19
Utility
Methods and Compositions for High Sensitivity Detection of Biothreat Pathogens
24 Nov 22
Provided herein are methods of amplifying and detecting biothreat pathogens in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).
Jessica Lee SNYDER, Daniel GAMERO, Robert Patrick SHIVERS, Kristen ROBERTS, Joseph MARTURANO, Thomas J. LOWERY, Jr., Roger SMITH, Brendan John MANNING
Filed: 10 Jun 20
Utility
Methods and Compositions for Comprehensive and High Sensitivity Detection of Pathogens and Drug Resistance Markers
3 Nov 22
Provided herein are methods of amplifying and detecting pathogens and drug resistance markers (e.g., antibiotic resistance genes) in complex samples (e.g., blood), as well as related panels and compositions (e.g., primers, probes, magnetic particles, systems, cartridges, and kits).
Jessica Lee SNYDER, Joseph MARTURANO, Sandy ESTRADA, Robert Patrick SHIVERS, Roger SMITH, Brendan John MANNING, Thomas J. LOWERY, Jr., Daniel GAMERO, Mohamed Nabuan NAUFER, Kelly N. BURGESS
Filed: 19 Jun 20
Utility
Methods and Compositions for High Sensitivity Sequencing In Complex Samples
8 Sep 22
Provided herein are methods of detecting and sequencing target nucleic acids in complex samples (e.g., blood), as well as related panels and compositions (e.g., systems, cartridges, and kits).
Jessica Lee SNYDER, Brendan John MANNING, Christopher STEELE, Roger SMITH, Heidi Susanne GIESE, Yin Shan Cathy WONG, Daniel GAMERO, Thomas J. LOWERY, Jr.
Filed: 10 Sep 19
Utility
NMR Methods and Systems for the Rapid Detection of Tick-borne Pathogens
21 Jul 22
The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
Ulrich Hans THOMANN, Lori Anne NEELY, Rahul Krishan DHANDA, Frédéric SWEENEY, Thomas Jay LOWERY, JR., Jessica Ann TOWNSEND, Jessica Lee SNYDER, Heidi Susanne GIESE, Cheryl Ann BANDOSKI-GRALINSKI, Daniella Lynn LOGAN
Filed: 5 Apr 22
Utility
NMR methods and systems for the rapid detection of tick-borne pathogens
10 May 22
The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.
Ulrich Hans Thomann, Lori Anne Neely, Rahul Krishan Dhanda, Frédéric Sweeney, Thomas Jay Lowery, Jr., Jessica Ann Townsend, Jessica Lee Snyder, Heidi Susanne Giese, Cheryl Ann Bandoski-Gralinski, Daniella Lynn Logan
Filed: 21 Jan 16
Utility
NMR Detection of Coagulation Time
17 Mar 22
The invention relates to detecting coagulation and coagulation-related activities including agglutination and fibrinolysis of samples.
Sonia TAKTAK, Brian M. MOZELESKI, Thomas J. LOWERY, JR.
Filed: 6 Apr 21
Utility
Compositions and methods for detection of candida species
24 Aug 21
The invention features compositions and methods for the detection of Candida species in biological samples, such as human tissue samples.
Lori Anne Neely
Filed: 12 Jan 17
Utility
NMR Systems and Methods for the Rapid Detection of Analytes
17 Jun 21
This invention features systems and methods for the detection of analytes, and their use in the treatment and diagnosis of disease.
Lori Anne NEELY, Mark John AUDEH, Rahul DHANDA, Marilyn Lee FRITZEMEIER, Daniella Lynn PLOURDE, Charles William RITTERSHAUS
Filed: 28 Jul 20
Utility
NMR Device for Detection of Analytes
18 Feb 21
This invention relates generally to detection devices having one or more small wells each surrounded by, or in close proximity to, an NMR micro coil, each well containing a liquid sample with magnetic nanoparticles that self-assemble or disperse in the presence of a target analyte, thereby altering the measured NMR properties of the liquid sample.
W. David Lee
Filed: 25 Mar 20
Utility
Methods and Systems for Amplification In Complex Samples
6 Jan 21
The invention features methods, systems, and cartridges for amplification of target nucleic acids in complex samples, for example, whole blood.
Ulrich Hans THOMANN, Jessica Lee SNYDER, Thomas Jay LOWERY, Jr.
Filed: 11 Apr 17
Utility
NMR Methods and Systems for the Rapid Detection of Candida Species
16 Sep 20
The invention features methods, systems, and panels for rapid detection of Candida species (e.g., Candida auris, Candida lusitaniae, Candida haemulonii, Candida duobushaemulonii, and Candida pseudohaemulonii) in biological samples (e.g., whole blood) and environmental samples (e.g., environmental swabs, e.g., surface swabs), and for diagnosis and monitoring of diseases, including Candidiasis and sepsis.
Brendan John MANNING, Jessica Lee SNYDER, Benjamin Nguyen CHANG, Trissha Ritsue HIGA, Robert Patrick SHIVERS, Yin Shan Cathy WONG, Thomas Jay LOWERY, Jr., Urvi VED, Daniel GAMERO
Filed: 16 May 18
Utility
Containers for Agitation of Liquid Samples and Methods of Use Thereof
19 Aug 20
The present invention relates to containers for holding liquid samples.
Adam SUCHOCKI, Mark John AUDEH, Matthew BLANCO, James Franklin CHEPIN, Vasiliki DEMAS, Marilyn Lee FRITZEMEIER, Thomas Jay LOWERY, JR., Michael MIN, Lori Anne NEELY, Charles William RITTERSHAUS, Hwa-Tang WANG, Parris WELLMAN
Filed: 20 Oct 19
Utility
NMR methods for monitoring blood clot formation
29 Jun 20
The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the clots being formed.
Thomas Jay Lowery, Jr., Vyacheslav Papkov, Walter W. Massefski, Jr., Rahul K. Dhanda, Edward Chris Thayer
Filed: 26 Sep 17
Utility
NMR methods for endotoxin analysis
13 Apr 20
The invention features a method of monitoring a clotting process by measuring a signal characteristic of the NMR relaxation of water in a sample undergoing endotoxi-induced clotting to produce NMR relaxation data and determining from the NMR relaxation data a magnetic resonance parameter of water in the sample characteristic of the level of endotoxin present in the sample.
Rahul K. Dhanda, Vyacheslav Papkov, Thomas Jay Lowery, Jr.
Filed: 19 Sep 12
Utility
Containers for agitation of liquid samples and methods of use thereof
25 Nov 19
The present invention relates to containers for holding liquid samples.
Adam Suchocki, Mark John Audeh, Matthew Blanco, James Franklin Chepin, Vasiliki Demas, Marilyn Lee Fritzemeier, Thomas Jay Lowery, Jr., Michael Min, Lori Anne Neely, Charles William Rittershaus, Hwa-Tang Wang, Parris Wellman
Filed: 7 Mar 17
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