25 patents
Utility
Methods Relating to Improving Accuracy of Capture Object-based Assays
6 Jul 23
Described herein are methods for improving the accuracy of capture object-based assays.
David C. Duffy, David M. Rissin, Matthew Fishburn, Andrew Rivnak, Purvish Patel
Filed: 8 Dec 22
Utility
Quantitative antibody test
27 Jun 23
The present disclosure relates to methods and compositions, e.g., kits, for quantitatively detecting an antibody of a subject to an infectious organism.
Andrew Ball, Lei Chang, Syrena Fernandes, Joe Johnson, Jeremy Lambert, Dawn Mattoon, Tatiana Plavina, David Wilson
Filed: 28 Apr 21
Utility
Methods and Systems Related to Highly Sensitive Assays and Delivering Capture Objects
6 Apr 23
Methods and systems for capture object-based assays, including for determining a measure of the concentration of an analyte molecule or particle in a fluid sample, are described.
David C. Duffy, Nicholas Collier, Cheuk W. Kan, Carmen I. Tobos, David M. Rissin, Alexander D. Wiener, Ray Meyer, Christopher Warwick, Roger Millington, Danielle M. Svancara
Filed: 13 Oct 22
Utility
Ultra-sensitive detection of molecules or particles using beads or other capture objects
4 Apr 23
The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample.
David C. Duffy, David M. Rissin, David R. Walt, David Fournier, Cheuk Kan
Filed: 11 Apr 19
Utility
Immunoassays for differential detection of clostridium difficile
6 Sep 22
Ultrasensitive and quantitative assays for detecting toxins of Clostridium difficile, which may involve digital ELISA, are provided.
Nira Pollock, Ciaran Kelly, David C. Duffy, Linan Song, Mingwei Zhao
Filed: 12 Feb 16
Utility
Methods of Determining a Treatment Protocol for And/or a Prognosis of a Patient's Recovery from a Brain Injury
4 Aug 22
The present invention, in some embodiments, generally relates to methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury.
David Wilson, John Henrik Zetterberg, Kaj Blennow, Jeffrey D. Randall
Filed: 18 Feb 22
Utility
Quantification of Neurofilament Light Chain In Physiological Samples
21 Jul 22
The present disclosure relates to immunoassays for NF-L performed on liquid samples derived from physiological fluids such as venous blood to detect the presence or absence of a physiological condition by quantifying one or a combination of NF-L determinations at concentrations indicative of the condition.
Edward Kevin HRUSOVSKY, David WILSON, Dandan SHAN, Lei CHANG, Linan SONG, Andreas JEROMIN, Carmen Ioana TOBOS, Purvish Prahlad PATEL
Filed: 9 Apr 19
Utility
Methods of Determining a Treatment Protocol for And/or a Prognosis of a Patient's Recovery from a Brain Injury
21 Jul 22
The present invention, in some embodiments, generally relates to methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury.
David Wilson, John Henrik Zetterberg, Kaj Blennow, Jeffrey D. Randall
Filed: 1 Feb 22
Utility
Materials and Kits Relating to Association of Reporter Species and Targeting Entities with Beads
30 Jun 22
Described herein are materials and kits for associating species with a surface of an object.
David M. Rissin, David C. Duffy
Filed: 28 Dec 20
Utility
Methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury
15 Mar 22
The present invention, in some embodiments, generally relates to methods of determining a treatment protocol for and/or a prognosis of a patient's recovery from a brain injury.
David Wilson, John Henrik Zetterberg, Kaj Blennow, Jeffrey D. Randall
Filed: 25 Jul 19
Utility
Methods and Kits for Detecting SARS-CORONAVIRUS-2 Antigen
17 Feb 22
The present disclosure relates to methods and compositions, e.g., kits, for assessing or detecting SARS-CoV-2 antigen(s), e.g., SARS-CoV-2 nucleocapsid protein (N-protein), in a sample or a blood sample, e.g., serum, plasma, dried blood spots (DBS) and/or a saliva sample.
Andrew Ball, Lei Chang, Syrena Fernandes, Kevin Hrusovsky, Joseph Johnson, Dawn Mattoon, Tatiana Plavina, Dandan Shan, David Wilson
Filed: 11 Aug 21
Utility
Systems, Devices, and Methods for Ultra-sensitive Detection of Molecules or Particles
3 Feb 22
Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid.
David Fournier, Todd Campbell, Cheuk W. Kan, John Lawson, Andrew Rivnak, Michael Kagan, David C. Duffy
Filed: 6 Aug 21
Utility
Quantitative Antibody Test
4 Nov 21
The present disclosure relates to methods and compositions, e.g., kits, for quantitatively detecting an antibody of a subject to an infectious organism.
Andrew Ball, Lei Chang, Syrena Fernandes, Joe Johnson, Jeremy Lambert, Dawn Mattoon, Tatiana Plavina, David Wilson
Filed: 28 Apr 21
Utility
Methods and Systems for Extending Dynamic Range In Assays for the Detection of Molecules or Particles
7 Oct 21
Described herein are systems and methods for extending the dynamic range of assay methods and systems used for determining the concentration of analyte molecules or particles in a fluid sample.
David M. Rissin, David Fournier, David C. Duffy
Filed: 23 Mar 21
Utility
Systems, devices, and methods for ultra-sensitive detection of molecules or particles
7 Sep 21
Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid.
David Fournier, Todd Campbell, Cheuk Kan, John Lawson, Andrew Rivnak, Michael Kagan, David C. Duffy
Filed: 14 Mar 18
Utility
Methods and systems for extending dynamic range in assays for the detection of molecules or particles
27 Apr 21
Described herein are systems and methods for extending the dynamic range of assay methods and systems used for determining the concentration of analyte molecules or particles in a fluid sample.
David M. Rissin, David Fournier, David C. Duffy
Filed: 10 Nov 17
Utility
Quantification of Biomarkers Present In Physiological Samples
8 Apr 21
The present disclosure relates to immunoassays for NF-L, GFAP, UCH L1, and Tau performed on liquid samples derived from physiological fluids such as venous blood to detect the presence or absence of a physiological condition by quantifying one or a combination of NF-L, GFAP, UCH L1, and Tau at concentrations indicative of the condition.
Edward Kevin HRUSOVSKY, David WILSON, Dandan SHAN, Lei CHANG, Linan SONG, Andreas JEROMIN, Carmen Ioana TOBOS, Purvish Prahlad PATEL
Filed: 9 Apr 19
Utility
Quantification of Biomarkers Present In Dried Physiological Samples
1 Apr 21
The present disclosure relates to digital immunoassays performed on diluted samples obtained from dried blood spots, for example dried capillary blood samples, to detect the presence or absence of a physiological condition by quantifying one or a combination of biomarkers at concentrations indicative of the condition.
Edward Kevin HRUSOVSKY, David WILSON, Dandan SHAN, Lei CHANG, Linan SONG, Andreas JEROMIN, Carmen Ioana TOBOS, Purvish Prahlad PATEL
Filed: 9 Apr 19
Utility
Ultra-sensitive Detection of Molecules or Particles Using Beads or Other Capture Objects
16 Dec 20
The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample.
David C. Duffy, David M. Rissin, David R. Walt, David Fournier, Cheuk W. Kan
Filed: 18 Jun 20
Utility
Methods and Systems for the Detection of Analyte Molecules
26 Aug 20
Methods and systems for the detection of analyte molecules are generally described.
David Wilson, David M. Rissin, Lei Chang, Andrew Rivnak, David C. Duffy
Filed: 19 Sep 18