Docoh
Loading...

NRIX Nurix Therapeutics

APP
Utility
Bifunctional Degraders of Hematopoietic Progenitor Kinase and Therapeutic Uses Thereof
18 Nov 21
The present disclosure provides bifunctional compounds as HPK1 degraders via ubiquitin proteosome pathway, and method for treating diseases modulated by HPK1.
Hunter P. Shunatona, Galen Paul Shearn-Nance, Scott A. Mitchell, John Buell
Filed: 5 May 21
APP
Utility
Bifunctional Compounds for Degrading BTK Via Ubiquitin Proteosome Pathway
1 Jul 21
This disclosure relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway.
Aileen KELLY, Arthur T. SANDS
Filed: 3 Dec 20
APP
Utility
CBL Inhibitors and Compositions for Expansion of Immune Cells
25 Mar 21
Methods and compositions using novel Cbl inhibitors enhancing expansion of immune cells to increase the efficacy of cell-based immunotherapeutics are disclosed.
Jennifa GOSLING, Arthur T. SANDS, Sarah Anne WHELAN, Michael LOTZE
Filed: 23 Sep 20
APP
Utility
CBL Inhibitors and Compositions for Use In Adoptive Cell Therapy
25 Mar 21
Methods and compositions using novel Cbl inhibitors for supporting engraftment of immune cells to increase the efficacy of cell-based immunotherapeutics are disclosed.
Jennifa GOSLING, Arthur SANDS, Sarah Anne WHELAN, Cristiana Guiducci
Filed: 23 Sep 20
APP
Utility
Substituted Benzyl-triazole Compounds for CBL-B Inhibition, and Further Uses Thereof
25 Feb 21
Compounds, compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed.
Arthur T. SANDS, Neil F. BENCE, Christoph W. ZAPF, Frederick COHEN, Chenbo WANG, Thomas CUMMINS, Hiroko TANAKA, Hunter SHUNATONA, Mario CARDOZO, Dahlia WEISS, Jennifa GOSLING
Filed: 26 Jun 20
APP
Utility
Cyano Cyclobutyl Compounds for CBL-B Inhibition and Uses Thereof
25 Feb 21
Compounds, compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed.
Arthur T. SANDS, Neil F. BENCE, Christoph W. ZAPF, Frederick COHEN, Chenbo WANG, Thomas CUMMINS, Hiroko TANAKA, Hunter SHUNATONA, Mario CARDOZO, Dahlia WEISS, Jennifa GOSLING
Filed: 15 May 20
APP
Utility
3-SUBSTITUTED Piperidine Compounds for CBL-B Inhibition, and Use of a CBL-B Inhibitor In Combination with a Cancer Vaccine And/or Oncolytic Virus
14 Oct 20
Compounds, compositions, and methods for use in inhibiting the E3 enzyme Cbl-b in the ubiquitin proteasome pathway are disclosed.
Arthur T. Sands, Neil F. Bence, Christoph W. Zapf, Frederick Cohen, Chenbo Wang, Thomas Cummins, Hiroko Tanaka, Hunter Shunatona, Mario Cardozo, Dahlia Weiss
Filed: 8 Apr 20
  • 1
Patents are sorted by USPTO publication date, most recent first