9 patents
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Dorsally-derived Oligodendrocyte Progenitor Cells from Human Pluripotent Stem Cells
4 May 23
Methods for differentiating human pluripotent stem cells to dorsal neuroectoderm progenitors and further to glial progenitor cells and oligodendrocyte progenitor cells (OPCs) using inhibitors of BMP signaling and MAPK/ERK signaling are provided.
Kento ONISHI, Nathan C. MANLEY, Craig R. HALBERSTADT, Erik M. WHITELEY
Filed: 2 Dec 22
Utility
Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
14 Mar 23
Methods for differentiating human pluripotent stem cells to dorsal neuroectoderm progenitors and further to glial progenitor cells and oligodendrocyte progenitor cells (OPCs) using inhibitors of BMP signaling and MAPK/ERK signaling are provided.
Kento Onishi, Nathan C. Manley, Craig R. Halberstadt, Erik M. Whiteley
Filed: 23 Jan 20
Utility
Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury
21 Sep 21
The present disclosure provides methods and compositions for making and using pluripotent stem cell-derived oligodendrocyte progenitor cells.
Edward D. Wirth, III, Jane S. Lebkowski, Nathan C. Manley
Filed: 10 May 19
Utility
Oligodendrocyte Progenitor Cell Compositions
24 Jun 21
Compositions comprising a population of oligodendrocyte progenitor cells (OPCs), as well as methods of making and using the same, are provided.
Erik Michael WHITELEY, Uzma SHOUKAT-MUMTAZ, Rashi SRIVASTAVA, Nathan Charles MANLEY, Casey Christopher CASE
Filed: 30 Mar 17
Utility
Suspension Culture of Human Embryonic Stem Cells
23 Dec 20
This disclosure provides an improved system for culturing human embryonic stem cells.
Ramkumar Mandalam, Yan Li, Isabelle Nadeau-Demers
Filed: 28 Apr 20
Utility
Dorsally-derived Oligodendrocyte Progenitor Cells from Human Pluripotent Stem Cells
22 Jul 20
Methods for differentiating human pluripotent stem cells to dorsal neuroectoderm progenitors and further to glial progenitor cells and oligodendrocyte progenitor cells (OPCs) using inhibitors of BMP signaling and MAPK/ERK signaling are provided.
Kento Onishi, Nathan C. Manley, Craig R. Halberstadt, Erik M. Whiteley
Filed: 22 Jan 20
Utility
Suspension culture of human embryonic stem cells
8 Jun 20
This disclosure provides an improved system for culturing human embryonic stem cells.
Ramkumar Mandalam, Yan Li, Isabelle Nadeau-Demers
Filed: 11 Feb 18
Utility
Pluripotent Stem Cell-derived Oligodendrocyte Progenitor Cells for the Treatment of Spinal Cord Injury
6 Nov 19
The present disclosure provides methods and compositions for making and using pluripotent stem cell-derived oligodendrocyte progenitor cells.
Edward D. Wirth, Jane S. Lebkowski, Nathan C. Manley
Filed: 9 May 19
Utility
Synthetic Surfaces For Culturing Stem Cell Derived Oligodendrocyte Progenitor Cells
6 Nov 19
Synthetic surfaces suitable for culturing stem cell derived oligodendrocyte progenitor cells contain acrylate polymers formed from one or more acrylate monomers.
Christopher Bankole Shogbon, Yue Zhou, Ralph Brandenberger
Filed: 3 Mar 19
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