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Regen BioPharma (RGBP)

Utility
Small molecule modulators of NR2F6 activity
8 Feb 22
Disclosed are compounds useful for alteration of NR2F6 activity.
David Koos, Thomas Ichim
Filed: 29 Nov 16
Utility
Enhanced Dendritic Cell Immune Activation by Combined Inhibition of NR2F6 with Cannibidiol
30 Dec 21
Cancer associated inflammation has been reported to act as an immune suppressive mechanism through augmentation of myeloid suppressor cells, as well as downregulation of T cell receptor (TCR) signaling through the cleavage of the CD3 zeta chain.
Thomas Ichim, David Koos
Filed: 29 Sep 20
Utility
Reduction of Post-surgery Cancer Metastasis by Combination of Cannabidiol and NR2F6 Inhibition
18 Nov 21
Disclosed are means of stimulating systemic immunity and reduction of post-surgery tumor metastasis through the concurrent intralymphatic inhibition of NR2F6 and treatment with cannabidiol.
Thomas Ichim, David Koos
Filed: 29 Sep 20
Utility
NR2F6 Inhibited Chimeric Antigen Receptor Cells
14 Oct 21
Disclosed are compositions of matter, cells, and methodologies for generation of chimeric antigen receptor (CAR) cells with inhibited or absent NR2F6 activity.
Thomas Ichim, David Koos
Filed: 14 Nov 16
Utility
Universal donor checkpoint inhibitor silenced/gene edited cord blood killer cells
12 Oct 21
Disclosed are compositions of matters, cells, and treatment protocols useful for induction of anticancer responses in a patient suffering from cancer.
Thomas Ichim, David Koos, Harry Lander
Filed: 21 Apr 17
Utility
Antigen specific mRNA cellular cancer vaccines
17 Aug 21
Disclosed are antigen specific cancer vaccines in which immunogenic epitopes are produced intracellularly by administration of modified mRNA encoding said immunogenic epitopes.
David Koos, Thomas Ichim
Filed: 23 May 16
Utility
Methods and means of generating IL-17 associated antitumor effector cells by inhibition of NR2F6 inhibition
6 Jul 21
Disclosed are means, methods, and compositions of matter useful for generation of cancer inhibitory effector cells producing interleukin-17 (IL-17).
David Koos, Thomas Ichim, Santosh Kesari
Filed: 13 Feb 17
Utility
Stimulation of T Regulatory Cells by Cannabidiol As a Means of Treating Arthritis and Autoimmunity
4 Mar 21
Disclosed are means, methods, and compositions of matter for stimulation of T regulatory (Treg) cells by cannabidiol.
Thomas Ichim, David Koos
Filed: 2 Sep 20
Utility
Small Molecule Modulators of NR2F6 Activity
27 Nov 19
Disclosed are compounds useful for alteration of NR2F6 activity.
David KOOS, Thomas ICHIM
Filed: 28 Nov 16
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