4 patents
Utility
miR29 MIMICS FOR THE TREATMENT OF OCULAR FIBROSIS
2 Dec 20
Provided herein are double-stranded, chemically-modified oligonucleotide mimetics of miR-29 for use in treating ocular diseases or disorders associated with ocular fibrosis, and ocular fibrotic conditions.
Corrie Lynn GALLANT-BEHM, Aimee JACKSON, Stephanie PROPP, Paul D. RUBIN
Filed: 29 Nov 18
Utility
Polynucleotide Conjugates and Uses Thereof
7 Oct 20
Provided herein are polynucleotide conjugates comprising a polynucleotide and an agent, wherein the polynucleotide comprises a synthetic double stranded miR-29 mimic and the agent facilitates the delivery of the polynucleotide to a cell type or tissue type involved in fibrosis or inflammation.
Subhadeep Roy, Kurt Vagle, Kevin Rigby, Rusty L. Montgomery
Filed: 4 Mar 20
Utility
Methods for Treating Cutaneous T-cell Lymphoma (CTCL) with MIR-155 Inhibitors
2 Sep 20
The present invention provides compositions and methods for treating cutaneous T-cell lymphoma (CTCL) with intralesional administration of one or more miR-155 inhibitors.
Aimee L. JACKSON, William S. MARSHALL
Filed: 6 Jul 17
Utility
Oligonucleotide Compositions and Uses Thereof
27 Nov 19
The present invention provides oligonucleotide inhibitors of miR-155 and compositions thereof.
David RODMAN, Anita SETO, Christina DALBY, Aimee JACKSON, Xuan BEATTY
Filed: 11 Apr 19
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