70 patents
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
16 Jan 24
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 27 Sep 22
Utility
Compositions and Methods of Treating Muscle Dystrophy
14 Dec 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
Venkata Ramana DOPPALAPUDI, Michael David HOOD, Rob BURKE, Michael Caramian COCHRAN, Beatrice Diana DARIMONT, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 31 May 23
Utility
Anti-transferrin receptor antibodies and uses thereof
5 Dec 23
Disclosed herein, in certain embodiments, are anti-transferrin receptor antibodies, anti-transferrin receptor antibody conjugates, and pharmaceutical compositions which comprise the anti-transferrin receptor antibodies or conjugates.
Beatrice Diana Darimont, Venkata Ramana Doppalapudi, Rachel Johns
Filed: 28 Apr 21
Utility
Antibody Oligonucleotide Conjugate Compositions and Methods of Inducing DMD Exon 44 Skipping
16 Nov 23
Disclosed herein are antibody oligonucleotide conjugates and pharmaceutical compositions that induce an alteration in an incorrectly spliced dystrophin mRNA transcript to induce exon 44 skipping.
Beatrice Diana DARIMONT, Usue ETXANIZ IRIGOIEN, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Isaac MARKS, Tyler ALBIN
Filed: 4 Apr 23
Utility
Compositions and Methods of Treating Facioscapulohumeral Muscular Dystrophy
26 Oct 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
Barbora MALECOVA, Rob BURKE, David SALA CANO, Beatrice Diana DARIMONT
Filed: 4 Nov 22
Utility
Compositions and Methods of Treating Pompe Disease
19 Oct 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Pompe Disease.
Gulin Erdogan MARELIUS, Beatrice Diana DARIMONT, Yunyu SHI
Filed: 4 May 21
Utility
Compositions and Methods of Treating Facioscapulohumeral Muscular Dystrophy
14 Sep 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
Barbora MALECOVA, Rob BURKE, David SALA CANO, Beatrice Diana DARIMONT
Filed: 4 Nov 22
Utility
Compositions and Methods of Treating Facioscapulohumeral Muscular Dystrophy
7 Sep 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
Barbora MALECOVA, Rob BURKE, David SALA CANO, Beatrice Diana DARIMONT
Filed: 4 Nov 22
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
1 Aug 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 12 Oct 21
Utility
Nucleic Acid-polypeptide Compositions and Uses Thereof
27 Jul 23
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer.
Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, David Sai-Ho CHU, Joel Daniel ARIAS, Rob BURKE
Filed: 19 Dec 22
Utility
Compositions and methods of treating muscle dystrophy
25 Jul 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
Venkata Ramana Doppalapudi, Michael David Hood, Rob Burke, Michael Caramian Cochran, Beatrice Diana Darimont, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 8 Aug 22
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
29 Jun 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 27 Sep 22
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
29 Jun 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 17 Nov 22
Utility
Compositions and Methods of Treating Facioscapulohumeral Muscular Dystrophy
23 Mar 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating facioscapulohumeral muscular dystrophy (FSHD).
Barbora MALECOVA, Rob BURKE, Beatrice Diana DARIMONT, David SALA CANO
Filed: 15 Sep 22
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
21 Feb 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 1 Sep 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
16 Feb 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 25 Aug 22
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
14 Feb 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 17 Nov 21
Utility
Nucleic acid-polypeptide compositions and uses thereof
14 Feb 23
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer.
Venkata Ramana Doppalapudi, Michael Caramian Cochran, David Sai-Ho Chu, Joel Daniel Arias, Rob Burke
Filed: 5 Jun 20
Utility
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
17 Jan 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
Filed: 12 Mar 21
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
17 Jan 23
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 1 Sep 21