70 patents
Page 2 of 4
Utility
Compositions and Methods of Treating Muscle Dystrophy
29 Dec 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
Venkata Ramana DOPPALAPUDI, Michael David HOOD, Rob BURKE, Michael Caramian COCHRAN, Beatrice Diana DARIMONT, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 8 Aug 22
Utility
Nucleic Acid-polypeptide Compositions and Uses Thereof
15 Dec 22
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Joel Daniel ARIAS, David Sai-Ho CHU, Michael Caramian COCHRAN, Rob BURKE, Philip KOVACH, Barbora MALECOVA
Filed: 30 Jun 21
Utility
Compositions and methods of treating Facioscapulohumeral muscular dystrophy
13 Dec 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating Facioscapulohumeral muscular dystrophy.
Barbora Malecova, Rob Burke, David Sala Cano, Beatrice Diana Darimont
Filed: 12 Mar 21
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
15 Nov 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 17 Nov 21
Utility
Nucleic Acid-polypeptide Compositions and Uses Thereof
13 Oct 22
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a polynucleic acid molecule and a polymer.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Rachel Elizabeth JOHNS, Palani BALU, Rob BURKE, Beatrice Diana DARIMONT
Filed: 5 May 21
Utility
Nucleic Acid-polypeptide Compositions and Methods of Inducing Exon Skipping
6 Oct 22
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
Filed: 17 Jun 22
Utility
Compositions and methods of treating muscle dystrophy
20 Sep 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle dystrophy (DM1).
Venkata Ramana Doppalapudi, Michael David Hood, Rob Burke, Michael Caramian Cochran, Beatrice Diana Darimont, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 26 Mar 21
Utility
Nucleic acid-polypeptide compositions and methods of inducing exon skipping
2 Aug 22
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
Filed: 31 Aug 21
Utility
Nucleic Acid Compositions and Methods of Multi-exon Skipping
28 Jul 22
Disclosed herein are oligonucleotide conjugates and pharmaceutical compositions for inducing multi-exon skipping.
Beatrice Diana DARIMONT, Yunyu SHI, Michael Caramian COCHRAN, Andrew John GEALL
Filed: 24 Apr 20
Utility
Nucleic acid-polypeptide compositions and uses thereof
21 Jun 22
Disclosed herein are compositions and pharmaceutical formulations that comprise a binding moiety conjugated to a modified polynucleic acid molecule and a polymer.
Andrew John Geall, Venkata Ramana Doppalapudi, Joel Daniel Arias, David Sai-Ho Chu, Michael Caramian Cochran, Rob Burke, Philip Kovach, Barbora Malecova
Filed: 30 Jun 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
5 May 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 17 Nov 21
Utility
Nucleic acid-polypeptide compositions and methods of inducing exon skipping
26 Apr 22
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
Filed: 31 Aug 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
31 Mar 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 12 Oct 21
Utility
Nucleic Acid-polypeptide Compositions and Methods of Inducing Exon Skipping
10 Mar 22
Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
Filed: 31 Aug 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
3 Mar 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 17 Nov 21
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
22 Feb 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 17 Sep 20
Utility
Compositions and methods of treating muscle atrophy and myotonic dystrophy
15 Feb 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John Geall, Venkata Ramana Doppalapudi, David Sai-Ho Chu, Michael Caramian Cochran, Michael Hood, Beatrice Diana Darimont, Rob Burke, Yunyu Shi, Gulin Erdogan Marelius, Barbora Malecova
Filed: 26 Feb 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
10 Feb 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 1 Sep 21
Utility
Compositions and Methods of Treating Muscle Atrophy and Myotonic Dystrophy
10 Feb 22
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods for treating muscle atrophy or myotonic dystrophy.
Andrew John GEALL, Venkata Ramana DOPPALAPUDI, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael HOOD, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Gulin Erdogan MARELIUS, Barbora MALECOVA
Filed: 12 Oct 21
Utility
Androgen Receptor Nucleic Acids and Uses Thereof
3 Feb 22
Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against androgen receptor.
Beatrice Diana DARIMONT
Filed: 21 Oct 21