8 patents
Utility
Vinylheterocycles as Rho-associated coiled-coil kinase (ROCK) inhibitors
3 Jan 23
The present invention provides compounds having formula (I): and pharmaceutically acceptable salts thereof, wherein Cy1, Cy2, Cy3, R, R1, R2, R3, A1 and A2 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which inhibiting ROCK1, ROCK2, or ROCK1/2 has a therapeutically useful role.
An-Hu Li, Dibyendu Dana, Dong Sung Lim, Satishkumar Gadhiya, Dawoon Jung, Prakash Narayan, Quaisar Ali, Swarnalatha Paka, Itzhak D. Goldberg
Filed: 31 Aug 18
Utility
Antifibrotic compounds and uses thereof
22 Nov 22
Bijoy Panicker, Rama K. Mishra, Dong Sung Lim, Lambertus J. W. M. Oehlen, Dawoon Jung
Filed: 2 Aug 19
Utility
Cytochrome P450 inhibitors and uses thereof
4 Oct 22
Bijoy Panicker
Filed: 25 Sep 20
Utility
Methods and agents for treating disease
6 Sep 22
Bijoy Panicker, Lambertus J. W. M. Oehlen
Filed: 23 Nov 20
Utility
Methods and compositions of small molecule modulators of hepatocyte growth factor (scatter factor) activity
26 Jan 21
Weizhong Cai
Filed: 4 Jan 19
Utility
Solid forms of (E)-3-[2-(2-thienyl)vinyl]-1H-pyrazole
28 Dec 20
The present disclosure provides solid forms of (E)-3-[2-(2-thienyl)vinyl]-1H-pyrazole, compositions thereof, and methods of making and using the same.
An-Hu Li, Satish Kumar Sakilam, Dong Sung Lim
Filed: 28 Jul 20
Utility
Methods and agents for treating disease
30 Nov 20
Bijoy Panicker, Lambertus J. W. M. Oehlen
Filed: 29 Apr 19
Utility
Cytochrome P450 inhibitors and uses thereof
10 Feb 20
Bijoy Panicker
Filed: 24 May 18
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