Concentrated Liquid Pharmaceutical Formulations of Furosemide and Methods of Administering the Same
31 Mar 22
Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer.
Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
Filed: 30 Jan 20
Pharmaceutical Formulations for Subcutaneous Administration of Furosemide
5 Feb 20
The present teachings relate to liquid pharmaceutical formulations of furosemide, where the pharmaceutical formulations include a molar excess of tris(hydroxymethyl)aminomethane to furosemide, have a pH in the range of 7 to 8.5, and a concentration of tris(hydroxymethyl)aminomethane greater than or equal to about 50 mM.
Scott A. Michaels, Pieter Muntendam, Glenn R. Larsen
Filed: 6 Mar 19
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