15 patents
Utility
Crystalline forms and methods of producing crystalline forms of a compound
17 Oct 23
Disclosed herein are methods of crystallizing the compound of Formula I, as well as crystalline forms thereof.
Brian Lian, Hiroko Masamune, Geoffrey Barker
Filed: 18 Mar 19
Utility
Compositions and methods for the treatment of metabolic and liver disorders
5 Sep 23
Disclosed herein are small molecule GIP/GLP-1 dual receptor agonist compositions, pharmaceutical compositions, the use and preparation thereof.
Brian Lian, Geoffrey E. Barker, Maureen Barnes, Kader Yagiz, Erland Stevens
Filed: 18 Nov 22
Utility
Compositions for the treatment of fibrosis
25 Jul 23
The present disclosure is directed to methods of treating fibrotic conditions by administration of TRβ agonists.
Brian Lian, Hiroko Masamune, Geoffrey E. Barker
Filed: 4 Jun 18
Utility
Compositions and Methods for the Treatment of Liver Disorders
20 Jul 23
The present disclosure is directed to FXR agonists, pharmaceutical compositions thereof, and methods of using the same for preventing, treating, or ameliorating fatty liver diseases such as steatosis, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis, either alone or in combination with thyroid receptor agonists.
Brian Lian, Geoffrey E. Barker, Kader Yagiz, Maureen Barnes, Erland Stevens
Filed: 7 Jun 21
Utility
Compositions and Methods for the Treatment of Metabolic and Liver Disorders
6 Apr 23
Disclosed herein are small molecule GIP/GLP-1 dual receptor agonist compositions, pharmaceutical compositions, the use and preparation thereof.
Brian Lian, Geoffrey E. Barker, Maureen Barnes, Kader Yagiz, Erland Stevens
Filed: 18 Nov 22
Utility
Use of Thyroid Beta-agonists
18 Aug 22
Methods useful for treating X-linked adrenoleukodystrophy are provided.
BRIAN LIAN, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
Filed: 6 May 22
Utility
Use of thyroid beta-agonists
7 Jun 22
Methods useful for treating X-linked adrenoleukodystrophy are provided.
Brian Lian, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
Filed: 24 Apr 17
Utility
Compositions and Methods for the Treatment of Liver Disorders
20 Jan 22
The present disclosure is directed toward the use of thyroid receptor agonists of pharmaceutically acceptable salts thereof, in combination with a second pharmaceutical agent for preventing, treating, or ameliorating fatty liver diseases such as steatosis, non-alcoholic fatty liver disease, and non-alcoholic steatohepatitis.
Brian Lian, Hiroko Masamune
Filed: 4 Dec 19
Utility
Compositions for the Treatment of Fibrosis and Inflammation
20 Jan 22
The present disclosure is directed to methods of treating fibrotic conditions and inflammation by administration of TRβ agonists.
Brian Lian, Hiroko Masamune, Geoffrey E. Barker
Filed: 4 Dec 19
Utility
Method of treating glycogen storage disease
21 Dec 21
The present disclosure provides methods and compositions for the treatment of hepatic symptoms of glycogen storage diseases through the administration of thyroid hormone receptor agonists.
Brian Lian
Filed: 17 Nov 17
Utility
Crystalline Forms and Methods of Producing Crystalline Forms of a Compound
28 Jan 21
Disclosed herein are methods of crystallizing the compound of Formula I, as well as crystalline forms thereof.
Brian Lian, Hiroko Masamune, Geoffrey Barker
Filed: 18 Mar 19
Utility
Conjoint Therapies with Inhibitors of Glucose Production
28 Oct 20
The present invention provides pharmaceutical compositions and methods for treating and/or preventing a metabolic condition.
Brian Lian
Filed: 7 Jul 20
Utility
Compositions for the Treatment of Fibrosis
10 Jun 20
The present disclosure is directed to methods of treating fibrotic conditions by administration of TRβ agonists.
Brian Lian, Hiroko Masamune, Geoffrey E. Barker
Filed: 3 Jun 18
Utility
Method of Treating Glycogen Storage Disease
13 Nov 19
The present disclosure provides methods and compositions for the treatment of hepatic symptoms of glycogen storage diseases through the administration of thyroid hormone receptor agonists.
Brian Lian
Filed: 16 Nov 17
Utility
Use of Thyroid Beta-agonists
23 Oct 19
Methods useful for treating X-linked adrenoleukodystrophy are provided.
Brian Lian, Rochelle Hanley, Misha Dinerman, Mark Erion, Serge Boyer, Hongjian Jiang
Filed: 23 Apr 17
- Prev
- 1
- Next
Patents are sorted by USPTO publication date, most recent first