9 patents
Utility
Compositions and methods for the treatment of viral infections
5 Dec 23
Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide.
James M. Balkovec, Daniel C. Bensen, Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Jason Cole, Quyen-Quyen Thuy Do, Simon Doehrmann, Wanlong Jiang, Thanh Lam, Alain Noncovich, Leslie W. Tari
Filed: 21 Apr 21
Utility
Compositions and methods for the treatment of fungal infections
21 Nov 23
The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form.
Kenneth Bartizal, Paul Daruwala, David Hughes, Martin Patrick Hughes, Navdeep B. Malkar, Balasingam Radhakrishnan, Anuradha Vaidya
Filed: 1 Dec 21
Utility
Dosing regimens for treatment of fungal infections
1 Aug 23
The disclosure features pharmaceutical compositions, methods, and kits featuring dosing regimens and CD101, or a pharmaceutical acceptable salt or neutral form thereof (e.g., CD101 acetate).
Kenneth Bartizal, Paul Daruwala, Jeffrey Brian Locke, Voon Ong, Taylor Sandison, Dirk Thye
Filed: 15 Mar 17
Utility
Dosing regimens for echinocandin class compounds
23 May 23
The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.
Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
Filed: 2 Jul 20
Utility
Synthesis of echinocandin antifungal agent
13 Dec 22
The present invention relates to echinocandin cyclopeptides and to methods for preparing echinocandin cyclopeptides.
David Hughes, Martin Patrick Hughes, Robert Michael Hughes, Balasingam Radhakrishnan, Yannick Borguet, Steven McIntyre
Filed: 14 Jun 19
Utility
Compositions and methods for the treatment of viral infections
29 Nov 22
Compositions and methods for the treatment of viral infections include conjugates containing inhibitors of viral neuraminidase (e.g., zanamivir, peramivir, or analogs thereof) linked to an Fc monomer, an Fc domain, and Fc-binding peptide, an albumin protein, or albumin-binding peptide.
Allen Borchardt, Thomas P. Brady, Zhi-Yong Chen, Thanh Lam, Leslie W. Tari
Filed: 21 Apr 21
Utility
Compositions and methods for the treatment of fungal infections
14 Dec 21
The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form.
Kenneth Bartizal, Paul Daruwala, David Hughes, Martin Patrick Hughes, Navdeep B. Malkar, Balasingam Radhakrishnan, Anuradha Vaidya
Filed: 11 Jul 18
Utility
Methods for preventing and treating pneumocystis infections
21 Sep 20
The disclosure relates to methods of prophylactic and therapeutic treatments of a Pneumocystis infection (i.e., an infection caused by Pneumocystis jirovecii) in a subject by administering to the subject a compound of any of formulas (I)-(III) (e.g., a salt of Compound 1, or a neutral form thereof).
Kenneth Bartizal, Paul Daruwala, Voon Ong, Maureen Roden, Taylor Sandison, Dirk Thye
Filed: 31 Jul 19
Utility
Dosing regimens for echinocandin class compounds
6 Jul 20
The invention features pharmaceutical compositions, methods, and kits featuring dosing gimens and oral dosage formulations for administration of echinocandin class compounds.
Balasingam Radhakrishnan, Kenneth Duke James, Jr., Anuradha Vaidya, Karen Polowy
Filed: 24 Jun 18
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