12 patents
Utility
Pharmaceutical composition comprising erythrocytes encapsulating a PLP-dependent enzyme and, a non-phosphate PLP precursor
4 Oct 22
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it.
Yann Godfrin, Vanessa Bourgeaux, Fabien Gay, Thomas Cortese
Filed: 22 Sep 20
Utility
Arginine Deiminase Encapsulated Inside Erythrocytes and Their Use In Treating Cancer and ARGINASE-1 Deficiency
23 Jun 22
The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy.
Emmanuelle DUFOUR, Manuel BLANC, Aurélien MEYZAUD
Filed: 8 Mar 22
Utility
Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
15 Mar 22
The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy.
Emmanuelle Dufour, Manuel Blanc, Aurélien Meyzaud
Filed: 29 Jun 18
Utility
Method of Treating a Mammal, Including Human, Against Cancer Using Methionine and Asparagine Depletion
10 Feb 22
The invention is related to a new method for treating liquid and solid cancers, in a mammal, including human, wherein methioninase is administered before asparaginase.
Karine AGUERA, Willy BERLIER, Fabien GAY, Yann GODFRIN
Filed: 24 Aug 21
Utility
Synergistic Combinations of Methionine Depletion Agents and Immune Checkpoint Modulators
30 Dec 21
The invention concerns a pharmaceutical composition, kit or fixed-dose combination comprising a methionine depletion agent (MDA), and an anti-cancer immune modulator (ACIM), for use in the treatment of a disease or condition in a subject or patient in need of treatment thereof.
Vanessa BOURGEAUX, Alexander SCHEER, Karine SENECHAL
Filed: 14 Nov 19
Utility
Method of treating a mammal, including human, against cancer using methionine and asparagine depletion
12 Oct 21
The invention is related to a new method for treating liquid and solid cancers, in a mammal, including human, wherein methioninase is administered before asparaginase.
Karine Aguera, Willy Berlier, Fabien Gay, Yann Godfrin
Filed: 2 Jan 17
Utility
METHOD OF INDUCING IMMUNE TOLERANCE BY ADMINISTERING ACTIVE PRINCIPLE-LOADING RBC's
2 Sep 21
The invention relates to a composition which induces, in a host, an immune tolerance to a peptidic or proteic active principle, said composition comprising red blood cells containing an active principle selected from the group consisting of a therapeutic peptide, polypeptide or protein, a peptidic or proteic autoantigen, peptide, polypeptide or protein inducing an allergic reaction and a transplantation peptidic or proteic antigen.
Yann GODFRIN, Alice BANZ
Filed: 5 Feb 21
Utility
Composition and Therapeutic Anti-tumour Vaccine
18 Mar 21
The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumour cells, and which comprises red blood cells containing said antigen.
Yann GODFRIN, Alice BANZ
Filed: 21 Aug 20
Utility
Pharmaceutical Composition Comprising Erythrocytes Encapsulating a Plp-dependent Enzyme And, a Non-phosphate PLP Precursor
14 Jan 21
The invention relates to a pharmaceutical composition containing a PLP-dependent enzyme and optionally its cofactor, pyridoxal phosphate (PLP), and/or a phosphate or non-phosphate precursor of PLP, its use as a drug, its production method and a therapeutic treatment method related to it.
Yann GODFRIN, Vanessa BOURGEAUX, Fabien GAY, Thomas CORTESE
Filed: 22 Sep 20
Utility
Pharmaceutical kit comprising erythrocytes encapsulating a PLP-dependent enzyme and, a non-phosphate PLP precursor
21 Sep 20
The invention relates to a pharmaceutical kit containing a) an injectable suspension of erythrocytes encapsulating a pyridoxal phosphate (PLP)-dependent enzyme and b) a non-phosphate PLP precursor.
Yann Godfrin, Vanessa Bourgeaux, Fabien Gay, Thomas Cortese
Filed: 12 Aug 18
Utility
Composition and therapeutic anti-tumour vaccine
21 Sep 20
The invention relates to a composition which induces, in a host, a cytotoxic cell response directed against cells expressing an antigen, in particular tumour cells, and which comprises red blood cells containing said antigen.
Yann Godfrin, Alice Banz
Filed: 23 Apr 18
Utility
Arginine Deiminase Encapsulated Inside Erythrocytes and Their Use In Treating Cancer and ARGINASE-1 Deficiency
12 Aug 20
The present invention is related to arginine deiminase encapsulated into erythrocytes for use in therapy.
Emmanuelle DUFOUR, Manuel BLANC, Aurélien MEYZAUD
Filed: 28 Jun 18
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