11 patents
Utility
Isoquinoline compounds and their use in treating AhR imbalance
28 Nov 23
The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof.
Channa K. Jayawickreme, Susan H. Smith, Cunyu Zhang, William Zuercher
Filed: 28 Oct 22
Utility
Micellic assemblies
25 Jul 23
Provided herein are micellic assemblies comprising a plurality of copolymers.
Patrick S. Stayton, Allan S. Hoffman, Anthony Convertine, Craig L. Duvall, Danielle Benoit, Robert Overell, Paul H. Johnson, Anna S. Gall, Mary G. Prieve, Amber E. E. Paschal, Charbel Diab, Priyadarsi De
Filed: 23 Sep 19
Utility
Branched peg molecules and related compositions and methods
27 Jun 23
Disclosed are branched PEG molecules, including branched PEG-lipids and branched-PEG proteins, as well as related compositions and methods for making branched PEG molecules.
Debashish Roy, Jean-Rene E. Ella-Menye, Sean D. Monahan, Pierrot Harvie, Anna Galperin, Michael E. Houston, Mary G. Prieve
Filed: 29 Dec 17
Utility
Topical pharmaceutical compositions
11 Apr 23
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase.
Sujatha D. Sonti, Joey Roger Thomas, Jon Lenn, Leandro Santos, Justin Whiteman, Michael Quinn Doherty, Mary Bedard, Piyush Jain
Filed: 21 Dec 18
Utility
Topical pharmaceutical compositions
4 Apr 23
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase.
Sujatha D. Sonti, Joey Roger Thomas, Jon Lenn, Leandro Santos, Justin Whiteman, Michael Quinn Doherty, Mary Bedard, Piyush Jain
Filed: 9 Nov 17
Utility
Topical pharmaceutical compositions
28 Mar 23
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase.
Sujatha D. Sonti, Joey Roger Thomas, Jon Lenn, Leandro Santos, Justin Whiteman, Michael Doherty, Mary Bedard, Piyush Jain
Filed: 30 Sep 19
Utility
Process for preparing tapinarof
7 Mar 23
The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein.
Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
Filed: 12 Feb 21
Utility
Use of Tapinarof for the treatment of chronic plaque psoriasis
28 Feb 23
Topical compositions and methods for using topical compositions comprising tapinarof to treat mild to moderate atopic dermatitis or plaque psoriasis are described herein.
John E. Kraus, James Lee
Filed: 22 Jul 22
Utility
Isoquinoline compounds and their use in treating AhR imbalance
10 Jan 23
The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof.
Channa K. Jayawickreme, Susan H. Smith, Cunyu Zhang, William Zuercher
Filed: 28 Jan 22
Utility
Use of tapinarof for the treatment of atopic dermatitis
15 Nov 22
Topical compositions and methods for using topical compositions comprising tapinarof to treat mild to moderate atopic dermatitis are described herein.
John E. Kraus, James Lee
Filed: 13 Nov 19
Utility
Topical pharmaceutical compositions
4 Oct 22
The present invention relates to topical pharmaceutical emulsion compositions comprising a therapeutically effective amount of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a pharmaceutically acceptable salt thereof, an oil phase, a water phase, a surfactant, and an antioxidant, and wherein the emulsion composition is homogeneous and/or the active is solubilized in the oil phase.
Sujatha D. Sonti, Joey Roger Thomas, Jon Lenn, Leandro Santos, Justin Whiteman, Michael Quinn Doherty, Mary Bedard, Piyush Jain
Filed: 21 Dec 18
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