29 patents
Utility
Compositions and Methods for Vaccination and the Treatment of Infectious Diseases
18 May 23
Methods of treating infectious diseases, such as a viral diseases, and methods of enhancing the effectiveness of a vaccine against an infectious disease, such as a viral disease, with an ICOS agonist, such as an anti-ICOS agonist antibody, are provided.
Christopher Harvey, Richard Murray, Robert Huebner
Filed: 19 Apr 21
Utility
Methods for the Treatment of Cancer
23 Mar 23
The invention provides methods for the treatment of cancer.
Yasmin RAMSAY, Daniel Joseph FELITSKY, Xiaoying XIAO, Hugh M. COLE
Filed: 13 Jan 21
Utility
Antibodies to LILRB2
23 Feb 23
Provided herein are various embodiments relating to antibodies that bind LILRB2.
Heather B. COHEN, Lauren Pepper MACKENZIE, Yasmin RAMSAY, Donald Raymond SHAFFER, Jeffrey Yan-Fei SMITH, Kristin Shanea O'MALLEY, Kevin Patrick GUAY
Filed: 13 Jun 22
Utility
Anti-PD-1 Antibodies and Uses Thereof
19 Jan 23
Provided herein are various embodiments relating to antibodies.
George Robert Mabry, III, Stephen Sazinsky
Filed: 7 Jun 22
Utility
Methods of Treating Cancer with Anti-PD-1 Antibodies
1 Dec 22
Methods of treating cancer with anti-PD-1 antibodies are provided.
Jian Xu
Filed: 4 Nov 20
Utility
Methods of Treating Cancer
20 Oct 22
The invention provides methods of treating cancer and methods for selecting treatment approaches for cancer.
Christopher HARVEY, Deborah LAW, Amanda Elizabeth HANSON, Martin Yu FAN
Filed: 31 Mar 22
Utility
Methods for the Treatment of Cancer
15 Sep 22
The invention provides methods of treating cancer and methods for selecting approaches for treatment of cancer.
Lara Lewis MCGRATH, Amy Jiayue MUELLER, Karen Suzanne BROWN, Benjamin Richards UMIKER, Yasmin Lucy RAMSAY
Filed: 9 Mar 22
Utility
Compositions and Methods for the Treatment of Cancer (Anti-ICOS Antibody Dosing)
8 Sep 22
Methods of treating cancer with particular doses of anti-ICOS antibodies are provided.
Jason Windham Reeves, Deborah Law, Christopher Harvey, Elizabeth G. Trehu, Lauren Pepper MacKenzie, Amit Deshpande, Jennifer S. Michaelson, Igor Feldman, Sriram Sathyanarayanan
Filed: 14 Dec 21
Utility
Anti-PD-1 antibodies and uses thereof
12 Jul 22
Provided herein are various embodiments relating to antibodies.
George Robert Mabry, III, Stephen Sazinsky
Filed: 10 Apr 20
Utility
Antibodies to LILRB2
14 Jun 22
Provided herein are various embodiments relating to antibodies that bind LILRB2.
Heather B. Cohen, Lauren Pepper Mackenzie, Donald Raymond Shaffer, Jeffrey Yan-Fei Smith
Filed: 14 Jul 20
Utility
Anti-ICOS Antibodies for the Treatment of Cancer
5 May 22
Methods of treating cancer with multiple doses of anti-ICOS antibodies and multiple doses of anti-CTLA4 antibodies are provided.
Christopher Harvey
Filed: 10 Mar 20
Utility
Methods of treating cancer in a subject having elevated ICOS and/or T-bet levels of CD+4 cells by administering an ICOS agonist
5 Apr 22
The invention provides methods of treating cancer and methods for selecting treatment approaches for cancer.
Christopher Harvey, Deborah Law, Amanda Elizabeth Hanson, Martin Yu Fan
Filed: 14 May 19
Utility
Methods and Compositions for the Treatment of Cancer and Infectious Diseases
9 Dec 21
The invention provides compositions and methods for the treatment of cancer and infectious diseases.
Christopher HARVEY, Deborah LAW, Amanda Elizabeth HANSON, Martin Yu FAN
Filed: 24 Oct 19
Utility
Methods of Treating Cancer
18 Nov 21
The present disclosure provides methods of treating cancer and methods for selecting treatment approaches for cancer.
Heather Hirsch, Deborah Law
Filed: 18 Oct 19
Utility
Methods of Treating Cancer
18 Nov 21
The present disclosure provides methods of treating cancer and methods for selecting treatment approaches for cancer.
Lara Lewis McGrath, Christopher Harvey, Deborah Law, Amanda Hanson
Filed: 25 Oct 19
Utility
Gene Signatures for Determining ICOS Expression
4 Nov 21
Gene expression signatures correlating to ICOS expression levels are provided.
Jason Windham Reeves, Igor Feldman, Christopher Harvey, Sriram Sathyanarayanan, Heather Hirsch, Lauren Pepper MacKenzie, Amit Deshpande, Stephen Sazinsky, Jennifer S. Michaelson, Kutlu Goksu Elpek
Filed: 5 Feb 21
Utility
Antibodies and Fusion Proteins That Bind to CCR8 and Uses Thereof
9 Sep 21
Provided herein are various embodiments relating to antibodies and fusion proteins and uses thereof.
Lara Lewis MCGRATH, Fabien DÉPIS, Changyun HU, Leonard G. PRESTA, Joshua Adam BUGGÉ
Filed: 9 Feb 21
Utility
Antibodies to ICOS
10 Jun 21
Provided herein are various embodiments relating to antibodies.
Stephen Sazinsky, Jennifer S. Michaelson, Sriram Sathyanarayanan, Kutlu Goksu Elpek
Filed: 16 Sep 20
Utility
Gene signatures for determining ICOS expression
6 Apr 21
Gene expression signatures correlating to ICOS expression levels are provided.
Jason Windham Reeves, Igor Feldman, Christopher Harvey, Sriram Sathyanarayanan, Heather Hirsch, Lauren Pepper MacKenzie, Amit Deshpande, Stephen Sazinsky, Jennifer S. Michaelson, Kutlu Goksu Elpek
Filed: 21 Oct 16
Utility
Anti-PD-1 Antibodies and Uses Thereof
23 Dec 20
Provided herein are various embodiments relating to antibodies.
George Robert Mabry, III, Stephen Sazinsky
Filed: 9 Apr 20