195 patents
Utility
Enhanced-flexibility transducer arrays for delivering TTFields (tumor treating fields)
16 Jan 24
A transducer array for use in tumor-treating fields (TTFields) therapy is particularly suited for use in treating abdominal or thoracic cancers.
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 8 Dec 21
Utility
Shifting of Transducer Array to Reduce Skin Irritation
11 Jan 24
A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrodes, the array configured to be positioned over the subject's body with a face of the array facing the subject's body, the array including electrode elements positioned in existing electrode positions arranged around a centroid of the array; at least one void space in the array capable of enclosing an areal footprint equivalent to at least 40% of an areal footprint of at least one existing electrode position, and superimposable on at least 40% of at least one existing electrode position by rotation of the array around the centroid; and a hydrocolloid material disposed in the at least one void space.
Noa Halavee, Boaz Marsault, Elie Yaacobi, Golan Bar-Tal, Nitzan Shany, Avishai Nahshoni
Filed: 22 Sep 23
Utility
Generating tumor treating fields (TTFields) with high uniformity throughout the brain
9 Jan 24
This application discloses configurations for arranging transducer arrays on a person's head to impose tumor treating fields (TTFields) in the brain at field strengths that are as uniform as possible throughout the entire brain.
Zeev Bomzon, Ariel Naveh, Ofir Yesharim
Filed: 28 Dec 21
Utility
Tumor Treating Field Transducers with Protective Border, and Apparatuses and Methods for Active Detection of Improper Transducer Configuration
4 Jan 24
A transducer apparatus for delivering tumor treating fields to a subject's body, including: a substrate; an electrode element coupled to the substrate; a layer of anisotropic material electrically coupled to the electrode element, wherein the electrode element is located between the substrate and the layer of anisotropic material having a front face and a back face, wherein the back face of the layer of anisotropic material faces the electrode element; a non-conductive material border disposed over an outer perimeter of the layer of anisotropic material, the non-conductive material border being electrically non-conductive, wherein, when viewed in a direction perpendicular to the front face of the layer of anisotropic material: an inner edge of the non-conductive material border overlaps a portion of the front face of the layer of anisotropic material, and an outer edge of the non-conductive material border extends outside the outer perimeter of the layer of anisotropic material.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO
Filed: 29 Jun 23
Utility
Delivering Tumor Treating Fields (TTFields) Using Implantable Transducer Arrays
4 Jan 24
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram WASSERMAN, Zeev BOMZON, Hadas Sara HERSHKOVICH, Ariel NAVEH, Moshe GILADI, Eilon KIRSON, Golan BAR-TAL, Tali VOLOSHIN-SELA
Filed: 15 Sep 23
Utility
Electrode Assembly for Applying Tumor Treating Fields (TTFields) that Includes a Plurality of Thermally Linked but Electrically Isolated Graphite Sheets
4 Jan 24
Alternating electric fields (e.g., TTFields) may be applied to a subject's body using electrode assemblies, each of which includes a plurality of graphite sheets (or sheets of another conductive anisotropic material) that are positioned adjacent to, but not touching, each other.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO
Filed: 29 Jun 23
Utility
Treating Acute Respiratory Distress Syndrome With Alternating Electric Fields
4 Jan 24
A method of treating acute respiratory distress syndrome (ARDS) in a subject by applying an alternating electric field (AEF) to a region of the subject's torso.
Moshe GILADI
Filed: 28 Jun 23
Utility
Adhesive Layer with Protective Border for Use In a Tumor Treating Fields Transducer
4 Jan 24
An adhesive layer for use in a transducer apparatus, the adhesive layer extending in an x-y plane and having an adhesive layer outer edge, the adhesive layer including: an adhesive matrix material; a plurality of electrically conductive particles embedded at least partially within the adhesive matrix material forming a conductive adhesive region of the adhesive layer; and at least one non-conductive edge portion comprising an adhesive devoid of electrically conductive particles, the at least one non-conductive edge portion being electrically non-conductive; wherein, when viewed in a direction perpendicular to the x-y plane, a first non-conductive edge portion is located adjacent to and extends along an outer edge of the conductive adhesive region and forms at least a portion of an outer perimeter of the adhesive layer.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK, David SHAPIRO
Filed: 29 Jun 23
Design
Electrode array
2 Jan 24
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 22 Jun 22
Design
Electrode array
2 Jan 24
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 1 Jul 22
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
2 Jan 24
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 14 Feb 23
Design
Electrode array
2 Jan 24
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 1 Jul 22
Design
Electrode array
2 Jan 24
Eilon Kirson, Yoram Wasserman, Noa Halavee
Filed: 22 Jun 22
Utility
Closed-Loop Technique to Reduce Electrosensation While Treating a Subject Using Alternating Electric Fields
28 Dec 23
A subject can be treated with an alternating electric field (e.g., TTFields) by applying the alternating electric field to a target region, and measuring nerve or muscle activity that is generated by the subject's body in response to the alternating electric field.
Kristen W. CARLSON
Filed: 27 Jun 23
Utility
Apparatus Comprising Dielectric Layer Coupled To Anisotropic Layer
28 Dec 23
An apparatus includes an outer adhesive layer comprising a conductive gel or conductive adhesive, at least one layer of anisotropic material, a layer of dielectric material, and a skin contact layer comprising a conductive gel or conductive adhesive.
David Shapiro, Yoram Wasserman, Stas Obuchovsky
Filed: 28 Jun 23
Utility
Methods For Treating Diabetes With Alternating Electric Fields
28 Dec 23
Disclosed are methods of treating that can be performed using alternating electric fields applied in a single direction or multiple directions.
Tali Voloshin-Sela, Lilach Avigdor
Filed: 27 Jun 23
Utility
Compositions, Systems, and Methods for Treating Cancer Using Tumor Treating Fields and Vegf Inhibitors
21 Dec 23
Compositions, systems, and methods for reducing viability of cancer cells and treating cancer, as well as preventing an increase of volume of a tumor present in a body of a living subject, are disclosed.
Tali Voloshin-Sela, Lilach AVIGDOR, Anat Klein-Goldberg
Filed: 20 Jun 23
Utility
Compositions And Methods For Treating With A Combination Of Alternating Electric Fields And Trastuzumab
21 Dec 23
Disclosed are methods of treating a subject in need thereof comprising applying an alternating electric field, at a frequency for a period of time, to a target site of the subject in need thereof, and administering trastuzumab to the target site of the subject in need thereof.
EunHo Kim
Filed: 31 May 22
Utility
Systems and Methods for Treating Conditions and Diseases Using Alternating Electric Fields and Crispr-cas System
21 Dec 23
Systems and methods are disclosed for inducing apoptosis and treating or reducing the occurrence of at least one condition, disease, disorder, or infection in a subject.
Tal KAN, Lilach AVIGDOR, Tali VOLOSHIN-SELA
Filed: 16 Jun 23
Utility
Compositions And Methods For Treating With A Combination Of Alternating Electric Fields And FGF Inhibitors
21 Dec 23
Disclosed are methods of treating a subject in need thereof comprising: applying alternating electric fields, at a frequency for a period of time, to a target site of the subject in need thereof; and administering one or more FGF inhibitors or FGFR inhibitors to the subject in need thereof.
Tali Voloshin-Sela, Lilach Avigdor, Anat Klein-Goldberg, Rom Paz, Elizabeth Moyal, Valerie Gouaze Andersson
Filed: 16 Jun 23