195 patents
Page 5 of 10
Utility
Arrays for Delivering Tumor Treating Fields (TTFields) with Selectively Addressable Sub-Elements
29 Dec 22
Tumor treating fields (TTFields) can be delivered to a subject's body at higher field strengths by switching off one or more electrode elements that are overheating without switching off other electrode elements that are not overheating.
Yoram WASSERMAN, Michael KRINITSKY, Sergey KIRILOV, Michael SHTOTLAND, Victor KAIKOV
Filed: 9 Jun 22
Utility
Perforated hydrogel configurations and methods of production and use thereof
27 Dec 22
Improved hydrogel configurations for use with a TTField-generating system is disclosed.
Richard Deslauriers
Filed: 6 Nov 20
Utility
Using alternating electric fields to increase cell membrane permeability
20 Dec 22
Certain substances (e.g., large molecules) that ordinarily cannot traverse the cell membrane of cells can be introduced into cells by applying an alternating electric field to the cell for a period of time, wherein the frequency of the alternating electric field is selected so that application of the alternating electric field increases permeability of the cell membrane.
Edwin Chang, Chirag B. Patel, Sanjiv S. Gambhir, Tali Voloshin-Sela, Yaara Porat, Moshe Giladi
Filed: 3 Jul 19
Utility
Methods of Treating and Preventing Cancer with Alternating Electric Fields, Radioactive Particles, and Systemic Therapy
15 Dec 22
Methods of treating and preventing cancer are provided.
William DOYLE
Filed: 10 Jun 22
Utility
Arrays for Longitudinal Delivery of TTFields to a Body
8 Dec 22
Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region.
Eilon KIRSON, Yoram WASSERMAN, Hadas Sara HERSHKOVICH, Zeev BOMZON
Filed: 11 Aug 22
Utility
Delivering tumor treating fields (TTFields) using implantable transducer arrays
18 Oct 22
Tumor treating fields (TTFields) can be delivered by implanting a plurality of sets of implantable electrode elements within a person's body.
Yoram Wasserman, Zeev Bomzon, Hadas Sara Hershkovich, Ariel Naveh, Moshe Giladi, Eilon Kirson, Golan Bar-Tal, Tali Voloshin-Sela
Filed: 26 Feb 20
Utility
Methods of Treating Neurodegenerative Disorders with Alternating Electric Fields
13 Oct 22
Methods of treating a neurodegenerative disorder in a subject are provided by applying alternating electric fields to the brain of the subject, optionally also administering a drug for treatment of the neurodegenerative disorder (e.g., Alzheimer's disease, Parkinson's disease, dementia) to the subject.
Tali VOLOSHIN-SELA, Lilach AVIGDOR, Eyal DOR-ON, Moshe GILADI, Hila FISHMAN
Filed: 8 Apr 22
Utility
Cage assembly for animal test subjects
11 Oct 22
A cage assembly can have at least one enclosure.
Shalom Strauss, Yoram Wasserman, Shiri Davidi, Roni Blat, Golan Bar Tal, Moshe Giladi, Michael Krinitsky, Michal Munster
Filed: 18 Dec 20
Utility
Impedance Tomography Using Electrodes of a Tumor Treating Fields (TTFields) System
6 Oct 22
Treatment of a target region using alternating electric fields (e.g., TTFields) may be planned by determining, based on a plurality of impedance measurements obtained during a first window of time, a first impedance at each of a plurality of voxels that correspond to the target region.
Yoram WASSERMAN
Filed: 31 Mar 22
Utility
Carrier For Elements Of Tumor-Treating Field Provision System And Systems And Methods Of Using Same
6 Oct 22
A system for applying Tumor-Treating Fields to a portion of a body of a subject is disclosed.
Francis X. Leonard II
Filed: 30 Mar 22
Utility
Assemblies containing two conductive gel compositions and methods of production and use thereof
4 Oct 22
An assembly for use in a TTField-generating system is disclosed that includes at least one electrode in combination with a polymerized conductive hydrogel and a liquid conductive hydrogel disposed on at least a portion of the polymerized hydrogel.
Richard Deslauriers
Filed: 22 Jan 21
Utility
Transducer Apparatuses for Delivering Tumor Treating Fields to a Subject's Body
29 Sep 22
A transducer apparatus for delivering tumor treating fields to a subject's body, the transducer apparatus including: an array of electrode elements comprising all electrode elements present on the transducer apparatus, the array configured to be positioned over the subject's body with a face thereof facing the subject's body; when viewed from a direction perpendicular to the face, a number of electrode elements of the array are peripheral electrode elements defining an outer perimeter, the peripheral electrode elements substantially surrounding all other electrode elements; for each pair of adjacent peripheral electrode elements, a distance between the pair is not more than 25% greater than a distance between any other pair of adjacent peripheral electrode elements; and for each peripheral electrode element, an angle formed between the peripheral electrode element and its two adjacent peripheral electrode elements is greater than 90 and less than 180 degrees and facing interior to the array.
Tal MARCIANO, Smadar ARVATZ, Boaz MARSAULT
Filed: 18 Mar 22
Utility
Methods and Apparatuses for Detecting and Responding to Changes In a Subject
29 Sep 22
A method of applying tumor treating fields to a region of interest of a subject's body corresponding to a tumor, the method including: alternately applying to the region of interest a first electric field between a first pair of locations of the subject's body and a second electric field between a second pair of locations of the subject's body; detecting a change in the region of interest of the subject's body; ceasing applying the first and second electric fields; selecting, based on the detected change, a third pair of locations of the subject's body and a fourth pair of locations of the subject's body, the third and fourth pairs of locations being different than the first and second pairs of locations; and alternately applying to the region of interest a third electric field between the third pair of locations and a fourth electric field between the fourth pair of locations.
Reuven Ruby SHAMIR, Yoram WASSERMAN, Zeev BOMZON, Oren PELES ZEEVI, Tal MARCIANO
Filed: 22 Mar 22
Utility
Arrays for longitudinal delivery of TTFields to a body
27 Sep 22
Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region.
Eilon Kirson, Yoram Wasserman, Hadas Sara Hershkovich, Zeev Bomzon
Filed: 4 Sep 19
Utility
Constructing a 3D Phantom with Liquid Hydrogel
22 Sep 22
A hydrogel phantom is herein described.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK
Filed: 18 Mar 22
Utility
Methods of Treating Disease by Skewing Macrophage Phenotype with Alternating Electric Fields
15 Sep 22
Methods of treating diseases and infections by applying alternating electric fields to tissues followed by administering a treatment for the disease or infection are provided.
Tali VOLOSHIN-SELA, Lilach AVIGDOR, Boris BRANT
Filed: 11 Mar 22
Utility
Compositions and Methods for Using Alternating Electric Fields to Disrupt Nanoparticles
15 Sep 22
Disclosed are methods comprising: administering a drug-loaded nanoparticle to a subject; and exposing a target site of the subject to an alternating electric field for a period of time, the alternating electric field having a frequency and field strength, and wherein the alternating electric field triggers the release of the drug from the drug-loaded nanoparticle at the target site of the subject.
Preshita Prafulla Desai
Filed: 11 Mar 22
Utility
Electrode Array and Methods of Production and Use Thereof
15 Sep 22
A method is described.
Yoram WASSERMAN, Stas OBUCHOVSKY, Nataliya KUPLENNIK
Filed: 14 Mar 22
Utility
Treatment assembly for providing tumor treating fields to animal test subjects
13 Sep 22
A treatment assembly can have an inner layer having an inner surface and an outer surface and defining a plurality of openings extending therethrough.
Michal Munster, Yoram Wasserman, Michael Shtotland, Shiri Davidi, Roni Blat, Golan Bar Tal, Moshe Giladi, Michael Krinitsky, Shalom Strauss
Filed: 18 Dec 20
Utility
Delivering Alternating Electric Fields (e.g., TTFields) to a Subject's Spinal Anatomy
8 Sep 22
This application discloses an improved approach for delivering alternating electric fields (e.g., TTFields) at a therapeutically effective strength to a target region of the spinal anatomy.
Zeev BOMZON, Ariel NAVEH, Ofir YESHARIM
Filed: 23 May 22