8 patents
Utility
Purification Processes for Polysaccharides and Polypeptide Conjugates Thereof
4 Jan 24
The present disclosure provides a process for purifying high-molecular weight bacterial polysaccharides (e.g., cell wall polysaccharides), and polypeptide-polysaccharide conjugates thereof, suitable for use in immunogenic compositions.
Christopher R. BEHRENS, Paresh AGARWAL, Lu YIN, Peter T. DAVEY, Angie A. SEDRA
Filed: 9 Aug 23
Utility
Group a Strep Immunogenic Compositions with Polysaccharide-protein Conjugates
21 Sep 23
The present disclosure provides immunogenic compositions comprising Group A Streptococcus (GAS) polypeptide antigens and at least one polypeptide-polysaccharide conjugate.
Jeffery C. FAIRMAN, Neeraj KAPOOR, Peter T. DAVEY, Angie A. SEDRA
Filed: 17 Aug 22
Utility
Periodontitis vaccine and related compositions and methods of use
18 Jul 23
An immunogenic composition, a periodontal vaccine formulation containing the immunogenic composition, and methods for treating or preventing periodontal disease are provided, where the methods involves administering an immunologically effective amount of the composition or vaccine formulation to a subject.
Jeffery Fairman
Filed: 5 May 21
Utility
Animal Product-free Culture of Streptococcus Bacteria
8 Dec 22
The present disclosure provides methods, compositions, and kits for in vitro cultivation of catalase-negative bacteria.
Peter DAVEY
Filed: 18 May 22
Utility
Optimized Cell-free Synthesis of Invasion Plasmid Antigen B and Related Compositions and Methods of Use
28 Apr 22
The present disclosure provides a cell-free method for synthesizing an Invasion Plasmid Antigen B (IpaB) antigen associated with a Shigella bacterium comprising exogenous addition of the purified chaperone protein IpgC to the cell-free synthesis mixture.
Neeraj KAPOOR, Jeffery C. FAIRMAN
Filed: 1 Oct 21
Utility
Periodontitis Vaccine and Related Compositions and Methods of Use
25 Nov 21
An immunogenic composition, a periodontal vaccine formulation containing the immunogenic composition, and methods for treating or preventing periodontal disease are provided, where the methods involves administering an immunologically effective amount of the composition or vaccine formulation to a subject.
Jeffery FAIRMAN
Filed: 5 May 21
Utility
Periodontitis vaccine and related compositions and methods of use
16 Nov 20
An immunogenic composition, a periodontal vaccine formulation containing the immunogenic composition, and methods for treating or preventing periodontal disease are provided, where the methods involves administering an immunologically effective amount of the composition or vaccine formulation to a subject.
Jeffery Fairman
Filed: 10 Oct 18
Utility
Conjugated Vaccines
19 Feb 20
Methods for the production of immunogenic compositions containing a non-natural amino acid are disclosed.
Jeffery C. FAIRMAN, Jon H. HEINRICHS, Wei CHAN, Olivier Jean GĂ©rard MARCQ, Christopher R. Behrens
Filed: 30 Jun 19
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