7 patents
Utility
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent
2 Jan 24
Hypertonic pharmaceutical compositions are disclosed.
Qi-Ying Hu, John Lee, Fuxin Shi
Filed: 21 Jun 21
Utility
Methods of otoprotection against platinum-based antineoplastic agents
4 Jul 23
Disclosed herein are methods for otoprotection against platinum-based antineoplastic agents by administering a thiosulfate salt to a subject in need thereof.
John Lee, John R. Soglia, Qi-Ying Hu, Fuxin Shi
Filed: 26 Oct 20
Utility
Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector systems
30 May 23
The disclosure features compositions and methods for the treatment of sensorineural hearing loss and auditory neuropathy, particularly forms of the disease that are associated with mutations in otoferlin (OTOF), by way of OTOF gene therapy.
Joseph Burns, Kathryn Ellis, Adam Palermo, Martin Schwander, Jonathon Whitton
Filed: 26 Apr 19
Utility
Expansion and differentiation of inner ear supporting cells and methods of use thereof
11 Oct 22
This disclosure relates to methods for expanding inner ear supporting cells (e.g., Lgr5+ inner ear supporting cells) and differentiating inner ear supporting cells (e.g., Lgr5+ inner ear supporting cells) to inner ear hair cells (e.g., atonal homolog 1 (Atoh1)+ inner ear hair cells) and the use of the inner hear supporting cells and hair cells, e.g., for identifying candidate therapeutic compounds for the treatment of hearing loss and balance loss.
Albert Edge, Michael Venuti, Agnieszka Czechowicz
Filed: 27 Jan 17
Utility
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent
27 Jul 21
Hypertonic pharmaceutical compositions are disclosed.
Qi-Ying Hu, John Lee, Fuxin Shi
Filed: 13 Jul 20
Utility
Methods of otoprotection against platinum-based antineoplastic agents
26 Oct 20
Disclosed herein are methods for otoprotection against platinum-based antineoplastic agents by administering a thiosulfate salt to a subject in need thereof.
John Lee, John R. Soglia, Qi-Ying Hu, Fuxin Shi
Filed: 30 May 19
Utility
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent
13 Jul 20
Hypertonic pharmaceutical compositions are disclosed.
Qi-Ying Hu, John Lee, Fuxin Shi
Filed: 18 Jul 19
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