9 patents
Utility
Multiepitope vaccine cassettes
3 Oct 23
Disclosed herein are compositions that include antigen-encoding nucleic acid sequences having multiple iterations of KRAS neoepitope-encoding sequences and/or lacking immunodominant epitopes.
Karin Jooss, Roman Yelensky, James Xin Sun, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin, Christine Denise Palmer, Monica Lane
Filed: 22 Apr 22
Utility
Modified adenoviruses
28 Feb 23
Compositions include modified adenoviruses.
Karin Jooss, Ciaran Daniel Scallan, Leonid Gitlin
Filed: 30 Nov 21
Utility
Alphavirus antigen vectors
29 Nov 22
Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject.
Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
Filed: 11 Mar 22
Utility
Alphavirus neoantigen vectors
22 Nov 22
Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject.
Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
Filed: 8 May 18
Utility
Alphavirus neoantigen vectors
23 Aug 22
Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject.
Wade Blair, Karin Jooss, Amy Rachel Rappaport, Ciaran Daniel Scallan, Leonid Gitlin
Filed: 8 May 18
Utility
Neoantigen identification using hotspots
1 Mar 22
A method for identifying neoantigens that are likely to be presented on a surface of tumor cells of a subject.
Brendan Bulik-Sullivan, Thomas Francis Boucher, Roman Yelensky
Filed: 3 May 19
Utility
Neoantigen identification, manufacture, and use
23 Nov 21
Disclosed herein is a system and methods for determining the alleles, neoantigens, and vaccine composition as determined on the basis of an individual's tumor mutations.
Roman Yelensky, Adnan Derti, Brendan Bulik-Sullivan, Jennifer Busby
Filed: 23 Nov 20
Utility
Neoantigen identification, manufacture, and use
23 Nov 20
Disclosed herein is a system and methods for determining the alleles, neoantigens, and vaccine composition as determined on the basis of an individual's tumor mutations.
Roman Yelensky, Adnan Derti, Brendan Bulik-Sullivan, Jennifer Busby
Filed: 5 Jun 18
Utility
Neoantigen identification, manufacture, and use
23 Nov 20
Disclosed herein is a system and methods for determining the alleles, neoantigens, and vaccine composition as determined on the basis of an individual's tumor mutations.
Roman Yelensky, Adnan Derti, Brendan Bulik-Sullivan, Jennifer Busby
Filed: 18 Jul 18
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