11 patents
Utility
Chemokine Receptor Modulators and Uses Thereof
12 Oct 23
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Parcharee Tivitmahaisoon, David J. Wustrow, Mikhail Zibinsky, Omar Robles
Filed: 5 Apr 23
Utility
Chemokine Receptor Modulators and Uses Thereof
4 May 23
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 20 May 22
Utility
Pyrazole Pyrimidine Compounds and Uses Thereof
29 Sep 22
Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.
Cyril Bucher, Adrian Dukes, Blanca Gomez, Hannah Haley, Dennis Hu, Jeffrey J. Jackson, Michelle Yoo Min Ko, Paul Leger, Anqi Ma, Andrew A. Ng, Daniel Poon, Omar Robles, Anton Shakhmin, Grant Shibuya, Parcharee Tivitmahaisoon, Vi-Anh Vu, David J. Wustrow, Mikhail Zibinsky
Filed: 14 Mar 22
Utility
Methods of Making Trans Isomeric Forms of G Protein-coupled Receptor Modulators
11 Aug 22
Disclosed herein, inter alia, methods of synthesis of trans isomeric forms of G protein-coupled receptor modulators of high trans isomeric purity.
Cyril Bucher, James P. Davidson, Jeffrey J. Jackson, Michelle Yoo Min Ko, Grant Shibuya, David J. Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 28 Jan 22
Utility
Ubiquitin-specific-processing Protease 7 (USP7) Modulators and Uses Thereof
14 Oct 21
Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
Jacob Bradley Schwarz, John Michael Ketcham, Maureen Kay Reilly, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, David Juergen Wustrow, Emily Karbarz, Xinping Han, Grant Shibuya, Jack Maung, Maksim Osipov
Filed: 5 Mar 20
Utility
Crystalline Forms of C-C Chemokine Receptor Type 4 Antagonist and Uses Thereof
13 May 21
Crystalline forms of a C-C chemokine receptor type 4 (CCR4) antagonist, oral dosage forms of same and methods of using and preparing same, are provided.
David J. ARNOLD, Omar ROBLES, Duane E. RUDISILL, David J. WUSTROW, Mikhail ZIBINSKY, Sami KARABORNI
Filed: 13 Nov 20
Utility
Chemokine Receptor Modulators and Uses Thereof
28 Oct 20
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 26 Apr 20
Utility
Chemokine Receptor Modulators and Uses Thereof
14 Oct 20
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 26 Apr 20
Utility
Chemokine Receptor Modulators and Uses Thereof
29 Jul 20
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of CCR4 activity.
Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky, Jeffrey J. Jackson
Filed: 27 Jan 20
Utility
Ubiquitin-specific-processing Protease 7 (USP7) Modulators and Uses Thereof
25 Mar 20
Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
Berenger Biannic, Xinping Han, Dennis X. Hu, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, David Juergen Wustrow, Kyle Young, Gene Cutler, Yamini Ohol-Gupta
Filed: 19 Sep 19
Utility
Pyrazolo-pyrimidin-amino-cycloalkyl Compounds and Their Therapeutic Uses
11 Dec 19
Disclosed herein are pyrozolo-pyrimidin-amino-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.
Minna H. T. Bui, Adrian O. Dukes, Xinping Han, Dennis X. Hu, Jeffrey J. Jackson, Yoo Min Ko, Paul R. Leger, Anqi Ma, Jack Maung, Andrew A. Ng, Akinori Okano, Omar Robles, Grant Shibuya, Hunter P. Shunatona, Jacob B. Schwarz, Anton A. Shakhmin, David J. Wustrow, Mikhail Zibinsky
Filed: 3 Jun 19
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