8 patents
Utility
Anticancer agents
22 Aug 23
Disclosed herein are therapeutic methods of administering compounds that modulate the C—C chemokine receptor type 4 (CCR4) for the treatment of Epstein Bar virus (EBV) positive cancers and malignancies.
Gene Cutler, William Yew-Wai Ho, Paul David Kassner, Silpa Suthram, Brian Russell Wong
Filed: 5 Nov 18
Utility
Chemokine receptor modulators and uses thereof
12 Jul 22
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 27 Apr 20
Utility
Chemokine receptor modulators and uses thereof
7 Dec 21
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 27 Apr 20
Utility
Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof
10 Aug 21
Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
Berenger Biannic, Xinping Han, Dennis X. Hu, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, David Juergen Wustrow, Kyle Young, Gene Cutler, Yamini Ohol-Gupta
Filed: 20 Sep 19
Utility
Pyrazolo-pyrimidin-amino-cycloalkyl compounds and their therapeutic uses
29 Jun 21
Disclosed herein are pyrozolo-pyrimidin-amino-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.
Minna H. T. Bui, Adrian O. Dukes, Xinping Han, Dennis X. Hu, Jeffrey J. Jackson, Yoo Min Ko, Paul R. Leger, Anqi Ma, Jack Maung, Andrew A. Ng, Akinori Okano, Omar Robles, Grant Shibuya, Hunter P. Shunatona, Jacob B. Schwarz, Anton A. Shakhmin, David J. Wustrow, Mikhail Zibinsky
Filed: 4 Jun 19
Utility
Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof
27 Jul 20
Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
Berenger Biannic, Xinping Han, Dennis X. Hu, John Michael Ketcham, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, Grant Shibuya, David Juergen Wustrow, Kyle Young
Filed: 12 Nov 18
Utility
Chemokine receptor modulators and uses thereof
15 Jun 20
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
Filed: 23 Jan 19
Utility
Chemokine receptor modulators and uses thereof
30 Mar 20
Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of CCR4 activity.
Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky, Jeffrey J. Jackson
Filed: 18 Nov 18
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