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ZEAL Zealand Pharma A/S.

APP
Utility
GLUCAGON-GLP-1-GIP Triple Agonist Compounds
25 Nov 21
The present invention relates to compounds which have agonist activity at the glucagon, GIP and GLP-1 receptors, and to their use in the treatment of metabolic disorders.
Rasmus JUST, Ditte RIBER, Anne Pernille Tofteng SHELTON, Torben ØSTERLUND, Kate HANSEN, Lene JESSEN
Filed: 29 Jul 21
APP
Utility
Amylin Analogues
11 Nov 21
The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes.
Jesper Mosolff MATHIESEN, Jesper Skodborg VILLADSEN, Lise GIEHM, Henrik Kofoed MUNCH, Dieter Wolfgang HAMPRECHT, Alexander HEIM-RIETHER, Giacomo FOSSATI
Filed: 21 Jul 21
GRANT
Design
Medicament delivery device
9 Nov 21
Christopher Gregory, Geoffrey Jenkins, Matthew Johnson
Filed: 25 Feb 21
APP
Utility
Cyclic Peptides Multimers Targeting ALPHA-4-BETA-7 Integrin
21 Oct 21
Mohammed Monzur MORSHED, Sai Kumar CHAKKA, Jennifer L. HICKEY, Manuel Perez VAZQUEZ, Andrew ROUGHTON, Adam Paul KAFAL, Narendrakumar B. PATEL
Filed: 19 Apr 21
APP
Utility
GLUCAGON-LIKE-PEPTIDE-2 (GLP-2) Analogues
7 Oct 21
GLP-2 analogues are disclosed which comprise one of more substitutions as compared to [hGly2]GLP-2 and which improved biological activity in vivo and/or improved chemical stability, e.g., as assessed in in vitro stability assays.
Bjarne Due LARSEN, Yvette Miata PETERSEN
Filed: 21 Jan 21
APP
Utility
Cyclic Peptides Targeting ALPHA-4-BETA-7 Integrin
30 Sep 21
Manuel Perez VAZQUEZ, M. Monzur MORSHED, Jennifer L. HICKEY, Adam Paul KAFAL, James GILLARD, Narendra PATEL, Sai Kumar CHAKKA, Andrew L. ROUGHTON, Marc-André POUPART, Gaoqiang YANG
Filed: 26 Mar 21
GRANT
Utility
GLP-1/GLP-2 dual agonists
28 Sep 21
The invention relates to compounds having agonist activity at the GLP-1 (glucagon-like-peptide 1) and GLP-2 (glucagon-like peptide 2) receptors.
Bjarne Due Larsen, Lise Giehm, Alistair Vincent Gordon Edwards
Filed: 11 Dec 17
APP
Utility
Liquid Formulations of Glucagon Analogues
16 Sep 21
The present invention relates to formulations of glucagon analogues, or a pharmaceutically acceptable salt thereof and/or a derivative thereof; and their medical use, for example in the treatment of hypoglycaemia.
Jesper Skodborg VILLADSEN, Tine Elisabeth Gottschalk BØVING
Filed: 16 Mar 21
GRANT
Utility
Cyclic peptides multimers targeting alpha-4-beta-7 integrin
7 Sep 21
There is described herein, multimers comprising a plurality of compounds covalently linked together, the compounds independently being of formula (I).
Mohammed Monzur Morshed, Sai Kumar Chakka, Jennifer L. Hickey, Manuel Perez Vazquez, Andrew Roughton, Adam Paul Kafal, Narendrakumar B. Patel
Filed: 10 Nov 17
GRANT
Utility
Glucagon-GLP-1-GIP triple agonist compounds
7 Sep 21
The present invention relates to compounds which have agonist activity at the glucagon, GIP and GLP-1 receptors, and to their use in the treatment of metabolic disorders.
Rasmus Just, Ditte Riber, Anne Pernille Tofteng Shelton, Torben Østerlund, Kate Hansen, Lene Jessen
Filed: 4 Oct 18
GRANT
Utility
Acylated glucagon analogues
17 Aug 21
The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders.
Ditte Riber, Jakob Lind Tolborg, Dieter Wolfgang Hamprecht, Wolfgang Rist
Filed: 12 Sep 19
APP
Utility
CorrectedAcylated GLP-1/GLP-2 Dual Agonists
12 Aug 21
A compound having agonist activity at the GLP-1 (glucagon-like-peptide 1) and GLP-2 (glucagon-like peptide 2) receptors, and a pharmaceutical composition containing the compound or a pharmaceutically acceptable salt or solvate thereof in admixture with a pharmaceutically acceptable carrier, an excipient or a vehicle are provided.
Bjarne DUE LARSEN, Jonathan GRIFFIN, Lise GIEHM, Alistair Vincent Gordon EDWARDS
Filed: 6 Apr 20
GRANT
Utility
Cyclic peptides targeting alpha-4-beta-7 integrin
27 Jul 21
Manuel Perez Vazquez, M. Monzur Morshed, Jennifer L. Hickey, Adam Paul Kafal, James Gillard, Narendra Patel, Sai Kumar Chakka, Andrew L. Roughton, Marc-André Poupart, Gaoqiang Yang
Filed: 14 Nov 16
GRANT
Utility
Fragment synthesis of substituted cyclic peptides
29 Jun 21
Manuel Perez Vazquez, M. Monzur Morshed, Jennifer L. Hickey, Marc-André Poupart, Gaoqiang Yang, James Gillard, Adam Paul Kafal, Andrew L. Roughton
Filed: 14 Nov 16
GRANT
Utility
Glucagon analogues and methods of use
15 Jun 21
The invention provides materials and methods for the treatment of obesity and excess weight, diabetes, and other associated metabolic disorders.
Ditte Riber, Jakob Lind Tolborg, Dieter Wolfgang Hamprecht
Filed: 4 May 18
GRANT
Utility
GIP-GLP-1 dual agonist compounds and methods
18 May 21
The present invention relates to acylated GIP analogues which have dual GIP and GLP-1 activity, and their use in the treatment of metabolic disorders.
Anne Pernille Tofteng Shelton, Pia Nørregaard, Jacob Ulrik Fog, Carsten Boye Knudsen
Filed: 27 Aug 18
GRANT
Utility
GIP agonist compounds and methods
11 May 21
The present invention relates to acylated GIP analogues which have GIP agonist activity, and their use in the treatment of metabolic disorders.
Anne Pernille Tofteng Shelton, Pia Nørregaard, Maria Alexandrovna Deryabina, Bjarne Due Larsen, Jacob Ulrik Fog
Filed: 21 Feb 19
GRANT
Utility
Needle control and drug mixing systems for a fluid delivery device
27 Apr 21
A fluid delivery device comprises a housing having a base including a bottom surface; a locking assembly including a cartridge receiver configured to receive a cartridge, the cartridge having a fluid reservoir and a septum configured to be generally perpendicular to the bottom surface when the cartridge is engaged with the cartridge receiver; and a needle assembly having a needle, the needle having a delivery end, a fluid coupling end, and a central portion located between the delivery end and the fluid coupling end, the needle assembly configured to move in laterally relative to the base to a first position and vertically relative to the base to a second position.
Matthew P. Johnson, Christopher C. Gregory
Filed: 30 Jun 16
APP
Utility
Amylin Analogues
22 Apr 21
The present invention relates to amylin analogues and to their use in the treatment or prevention of a variety of diseases, conditions or disorders, including obesity, excess food intake and associated metabolic diseases such as diabetes.
Rasmus JUST, Oliver DEMMER, Lise GIEHM, Jesper Skodborg VILLADSEN, Henrik MUNCH, Jesper Mosolff MATHIESEN, Jolanta SKARBALIENE, Maria DERYABINA, Dieter Wolfgang HAMPRECHT
Filed: 6 Aug 20
GRANT
Design
Medicament delivery device
23 Mar 21
Christopher Gregory, Geoffrey Jenkins, Matthew Johnson
Filed: 1 Jul 20
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