40 patents
Page 2 of 2
Utility
Prodrugs of Riluzole and Their Method of Use
5 Aug 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffrey Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 18 Jan 21
Utility
Riluzole Prodrugs and Their Use
5 Aug 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffrey Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 1 Feb 21
Utility
Riluzole Prodrugs and Their Use
29 Jul 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffrey Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 18 Jan 21
Utility
Use of Riluzole Prodrugs to Treat Alzheimer's Disease
15 Jul 21
Disclosed are methods of treating Alzheimer's Disease by administering to a patient in need thereof a riluzole prodrug such as troriluzole.
Vladimir Coric, Robert Berman, Irfan Qureshi
Filed: 18 Jan 21
Utility
Riluzole prodrugs and their use
6 Jul 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffery Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 20 Nov 19
Utility
CGRP Antagonists for Treating Migraine Breakthrough
1 Jul 21
Disclosed are methods of treating breakthrough migraine in patients using breakthrough CGRP antagonists.
Vladimir Coric, Robert Croop
Filed: 17 Feb 21
Utility
Prodrugs of Riluzole and Their Method of Use
18 Mar 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Garry Robert Smith, Allen B. Reitz, Mark McDonnell, Suzie Chen, Matthew D. Vera, Benjamin E. Blass, Jeffrey Claude Pelletier, Venkata N. Velvadapu, Jay Edward Wrobel
Filed: 23 Nov 20
Utility
Sublingual Formulation of Riluzole
11 Feb 21
Disclosed is sublingual administration of riluzole.
Vladimir Coric, Robert Berman, Ronald S. Vladyka, Amgad Saleh, Danny Yu
Filed: 25 Oct 20
Utility
Riluzole prodrugs and their use
2 Feb 21
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jefferey Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 24 Jun 19
Utility
Use of Riluzole Prodrugs to Treat Ataxias
28 Jan 21
Disclosed are methods of treating ataxia by administering to a patient in need thereof a riluzole prodrug such as troriluzole.
Vladimir Coric, Robert Berman, Melissa Beiner, Gilbert L'Italien
Filed: 11 Nov 18
Utility
Rimegepant for CGRP Related Disorders
6 Jan 21
Disclosed are methods of treating CGRP related disorders, e.g., migraine, by administering to a patient in need thereof rimegepant or a pharmaceutically acceptable salt thereof.
Vladimir Coric, Robert Croop
Filed: 24 Mar 19
Utility
Rimegepant for CGRP Related Disorders
9 Dec 20
Disclosed are methods of treating CGRP related disorders, e.g., migraine, by administering to a patient in need thereof rimegepant or a pharmaceutically acceptable salt thereof.
Vladimir Coric, Robert Croop
Filed: 26 May 20
Utility
Prodrugs of riluzole and their method of use
23 Nov 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Garry Robert Smith, Allen B. Reitz, Mark McDonnell, Suzie Chen, Matthew D. Vera, Benjamin E. Blass, Jeffrey Claude Pelletier, Venkata N. Velvadapu, Jay Edward Wrobel
Filed: 20 Jan 20
Utility
Prodrugs of Lanicemine and Their Method of Use
23 Sep 20
Pharmaceutical compositions of the invention include substituted Lanicemine prodrugs useful for the treatment of conditions associated with dysregulation of NMDA receptor activity such as depression and depressive disorders through the release of Lanicemine, Prodrugs of Lanicemine have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release Lanicemine in the plasma via either an enzymatic or general biophysical release process.
Allen B. Reitz, Jeffery Claude Pelletier
Filed: 21 Nov 17
Utility
Riluzole Prodrugs and Their Use
16 Sep 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jefferey Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 23 Jun 19
Utility
Prodrugs of Riluzole and Their Method of Use
20 May 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Garry Robert Smith, Allen B. Reitz, Mark McDonnell, Suzie Chen, Matthew D. Vera, Benjamin E. Blass, Jeffery Claude Pelletier, Venkata N. Velvadapu, Jay Edward Wrobel
Filed: 20 Jan 20
Utility
Prodrugs of riluzole and their method of use
4 May 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffery Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 25 Feb 16
Utility
Riluzole Prodrugs and Their Use
18 Mar 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffery Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 19 Nov 19
Utility
Prodrugs of riluzole and their method of use
17 Feb 20
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Garry Robert Smith, Allen B. Reitz, Mark Mcdonnell, Suzie Chen, Matthew D. Vera, Benjamin E. Blass, Jeffery Claude Pelletier, Venkata N. Velvadapu, Jay Edward Wrobel
Filed: 3 Aug 17
Utility
Riluzole prodrugs and their use
25 Nov 19
Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole.
Jay Edward Wrobel, Allen B. Reitz, Jeffery Claude Pelletier, Garry Robert Smith, Haiyan Bian
Filed: 25 Feb 16