39 patents
Utility
Extracellular Vesicles from Prevotella
21 Dec 23
Provided herein are methods and compositions related to Prevotella EVs useful as therapeutic agents.
Brian Goodman, Baundauna Bose, Christopher J.H. Davitt, Sofia M.R. Carlton, William Caffry, Hank Wu
Filed: 18 Jan 23
Utility
Solid Dosage Forms of Bacteria
23 Nov 23
Methods and compositions related to solid dosage forms that facilitate the oral delivery of bacteria and/or agents of bacterial origin are provided herein.
Syed Altaf, Ruiming Huang, Robert Ward, Ryan Wilson, Chun Zhang
Filed: 17 Sep 21
Utility
Solid Dosage Forms Containing Bacteria and Microbial Extracellular Vesicles
9 Nov 23
Enterically-coated solid dosage forms containing a pharmaceutical agent which includes bacteria and/or microbial extracellular vesicles (mEVs) are provided.
Christopher J. H. Davitt, Brian Goodman, Syed Altaf
Filed: 23 Dec 20
Utility
Compositions and Methods for Treating Diseases and Disorders Using Fournierella Massiliensis
28 Sep 23
Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Fournierella massiliensis that are useful as therapeutic agents.
Alicia Ballok, Loise Francisco-Anderson, Kevin Huynh, Valeria Kravitz, Audrey McBride, Tyler Rommel, Maria Sizova
Filed: 11 Jun 21
Utility
Veillonella Parvula Strain As an Oral Therapy for Neuroinflammatory Diseases
7 Sep 23
Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Veillonella parvula Strain A that are useful as therapeutic agents, such as for treating neuroinflammation.
Mark Bodmer, Andrea Itano, Holly Ponichtera
Filed: 20 Jul 21
Utility
Prevotella Histicola Strain C As an Oral Therapy for Inflammatory Diseases
17 Aug 23
Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Prevotella histicola Strain C that are useful as therapeutic agents, e.g., for treating inflammatory diseases (e.g., a neuroinflammatory disease).
Mark Bodner, William Caffry, Taylor A. Cormack, Valeria Kravitz, Alline Pacheco, Holly Ponichtera, Kritika Ramani, Maria Sizova, Leslie Wardwell-Scott
Filed: 20 Jul 21
Utility
Compositions and Methods for Treating Diseases and Disorders Using Harryflintia Acetispora
13 Jul 23
Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Harryflintia acetispora that are useful as therapeutic agents.
Alicia Ballok, Loise Francisco-Anderson, Kevin Huynh, Valeria Kravitz, Audrey McBride, Tyler Rommel, Maria Sizova
Filed: 11 Jun 21
Utility
Methods and Compositions for Culturing Hemoglobin-dependent Bacteria
13 Jul 23
Provided herein are compositions and methods related to culturing bacteria (such as hemoglobin-dependent bacteria) with a heme-containing polypeptide (such as a heme-containing polypeptide that is not sourced from an animal and/or can be recombinantly produced).
Valeria Kravitz, Manas Ray, Maria Sizova
Filed: 25 Nov 20
Utility
Bacterial Extracellular Vesicles
6 Jul 23
Provided herein are methods and compositions related to EVs useful as therapeutic agents.
Brian Goodman, Baundauna Bose, Christopher J.H. Davitt
Filed: 2 Dec 22
Utility
Probiotic compositions containing clostridiales for inhibiting inflammation
28 Mar 23
Pharmaceutical compositions containing microbial entities are described herein.
David Berry, Johanne Kaplan, Shaila Rahman
Filed: 13 Dec 18
Utility
Probiotic compositions containing clostridiales for inhibiting inflammation
21 Mar 23
Pharmaceutical compositions containing microbial entities are described herein.
David Berry, Johanne Kaplan, Shaila Rahman
Filed: 23 Aug 19
Utility
Compositions and Methods for Reducing Cytokine Expression
19 Jan 23
Provided herein are methods and compositions related to Prevotella bacteria for the reduction of IL-8, IL-6, IL-Iβ, and/C or TNFα expression and/or for the treatment of viral infections.
David Epstein, Duncan McHale
Filed: 26 Feb 21
Utility
Bacterial extracellular vesicles
13 Dec 22
Provided herein are methods and compositions related to EVs useful as therapeutic agents.
Brian Goodman, Baundauna Bose, Christopher J. H. Davitt
Filed: 10 Sep 18
Utility
Methods and Compositions for Anaerobic Bacterial Fermentation
17 Nov 22
Provided herein are methods and compositions related to fermentation of anaerobic bacteria.
Mehmedalija Jahic, Dacvid Emerson, Collin McKenna, Raashed Raziuddin
Filed: 21 May 20
Utility
Compositions and Methods of Treating Psoriasis and Atopic Dermatitis Using Prevotella Histicola
27 Oct 22
Provided herein are methods and compositions related to Prevotella bacteria useful as therapeutic agents, e.g., for the treatment of psoriasis or atopic dermatitis.
S. M. Abel, Kristie Barth, Mark Bodmer, Taylor A. Cormack, Tanmoy Ganguly, Humphrey Gardner, Andrea Itano, Duncan McHale, Mustafa Noor, Holly Ponichtera, Kritika Ramani, Peter Sandy
Filed: 4 Aug 20
Utility
Probiotic and Prebiotic Compositions, and Methods of Use Thereof for Modulation of the Microbiome
13 Oct 22
Probiotic compositions containing non-pathogenic microbial entities, e.g., bacterial entities, are described herein.
David Berry, Noubar B. Afeyan, Johanne Kaplan, Shaila Rahman
Filed: 26 Mar 21
Utility
Processed Microbial Extracellular Vesicles
22 Sep 22
Provided herein are methods and pharmaceutical compositions related to processed microbial extracellular vesicles (pmEVs) that can be useful as therapeutic agents.
Alicia Ballok, Mark Bodmer, Baundauna Bose, Sofia M. Carlton, Taylor A. Cormack, Christopher J.H. Davitt, Loise Francisco-Anderson, Brian Goodman, Andrea ltano, Nihal Okan, Holly Ponichtera, Erin B. Troy, Fabian B. Romano-Chernac, Maria Sizova
Filed: 11 Jun 20
Utility
Methods and Compositions for Culturing Hemoglobin-dependent Bacteria
25 Aug 22
Provided herein are methods and compositions related to culturing hemoglobin-dependent bacteria.
Valeria Kravitz, Maria Sizova
Filed: 31 Jul 20
Utility
Secreted Microbial Extracellular Vesicles
11 Aug 22
Provided herein are methods and pharmaceutical compositions related to secreted microbial extracellular vesicles (smEVs) that can be useful as therapeutic agents.
Alicia Ballok, Mark Bodmer, Baundauna Bosse, Sofia M. Carlton, Taylor A. Cormack, Christopher J. Davitt, Loise Francisco-Anderson, Brian Goodman, Andrea Itano, Nihal Okan, Holly Ponichtera, Erin B. Troy, Fabian B. Romano-Chernac, Maria Sizova
Filed: 11 Jun 20
Utility
Bacterial Membrane Preparations
21 Apr 22
Provided herein are methods and compositions related to membrane preparations (MPs) useful as therapeutic agents.
Brian Goodman, Baundauna Bose, Erin B. Troy
Filed: 21 Feb 20