9 patents
Utility
Compositions and Methods for Treating Galactosemia
2 Nov 23
The disclosure relates to methods for treating galactosemia and manifestations of galactosemia using aldose reductase inhibitors.
Shoshana SHENDELMAN
Filed: 23 Jan 23
Utility
Aldose Reductase Inhibitors for Treating Sorbitol Dehydrogenase Deficiency
20 Apr 23
The disclosure relates to methods for a genetic and/or metabolic disorder that alters sorbitol metabolism or causes over production of sorbitol, such as SDH deficiency, hereditary neuropathy using aldose reductase inhibitors.
Shoshana SHENDELMAN
Filed: 28 Oct 22
Utility
Compositions and methods for treating galactosemia
28 Feb 23
The disclosure relates to methods for treating galactosemia and manifestations of galactosemia using aldose reductase inhibitors.
Shoshana Shendelman
Filed: 27 Jul 18
Utility
Aldose Reductase Inhibitors for the Treatment of Acute Respiratory Distress Syndrome, Acute Lung Inflammation/injury, Cardiac Injury and Anti-viral Therapy
23 Feb 23
The disclosure relates to methods for treating acute respiratory distress syndrome (ARDS), acute lung inflammation (ALI), acute lung injury and/or cardiac injury (e.g., acute cardiac injury), treating an infection, reducing pathogen burden and/or inhibiting pathogen replication by administering to a subject in need thereof a therapeutically effective amount of an aldose reductase inhibitor.
Shoshana SHENDELMAN
Filed: 23 Sep 22
Utility
Aldose Reductase Inhibitors for Treatment of Phosphomannomutase 2 Deficiency
21 Jul 22
The disclosure relates to methods for treating PMM2-CDG using aldose reductase inhibitors.
Riccardo Perfetti, Shoshana SHENDELMAN
Filed: 7 Apr 22
Utility
Methods for Treating Cutaneous Aging
10 Mar 22
The disclosure relates to methods for treating cutaneous aging by administering to a subject in need thereof a therapeutically effective amount of an aldose reductase inhibitor.
Shoshana SHENDELMAN
Filed: 12 Feb 20
Utility
Inhibitors of Aldose Reductase
20 Jan 22
The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for promoting healthy aging of skin, the treatment of skin disorders, the treatment of cardiovascular disorders, the treatment of renal disorders, the treatment of angiogenesis disorders, such as cancer, treatment of tissue damage, such as non-cardiac tissue damage, the treatment of evolving myocardial infarction, the treatment of ischemic injury, and the treatment of various other disorders, such as complications arising from diabetes with the compounds and compositions of the invention.
Andrew Wasmuth
Filed: 29 Sep 21
Utility
Compositions and Methods for Treating Galactosemia
22 Jul 20
The disclosure relates to methods for treating galactosemia and manifestations of galactosemia using aldose reductase inhibitors.
Shoshana SHENDELMAN
Filed: 26 Jul 18
Utility
Aldose Reductase Inhibitors and Uses Thereof
29 Apr 20
The present invention relates to boronic acid and boronate ester compounds that are inhibitors of aldose reductase, and to compositions that contain the compounds and methods of using the compounds.
Shoshana Shendelman
Filed: 16 Apr 18
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