5 patents
Utility
Enzyme-cleavable Methadone Prodrugs and Methods of Use Thereof
25 May 23
The present disclosure provides methadone prodrugs, pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions comprise a methadone prodrug that provides enzymatically-controlled release of methadone, and an optional enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of methadone from the prodrug so as to attenuate enzymatic cleavage of the prodrug.
Lynn Kirkpatrick
Filed: 28 Sep 22
Utility
Compositions Comprising Enzyme-cleavable Prodrugs and Controlled Release Nafamostat and Methods of Use Thereof
15 Sep 22
Aspects of the present disclosure include pharmaceutical compositions, and their methods of use, where the pharmaceutical compositions include an active agent prodrug that provides enzymatically-controlled release of an active agent, and controlled release nafamostat or a pharmaceutically acceptable salt thereof.
Lynn Kirkpatrick
Filed: 8 Mar 22
Utility
Modified Release Compositions of Nafamostat and Methods of Using Same
15 Sep 22
Aspects of the present disclosure include a composition of nafamostat or a pharmaceutically acceptable salt thereof that provides for controlled release of nafamostat or pharmaceutically acceptable salt thereof to a subject for an extended period of time.
Lynn Kirkpatrick
Filed: 8 Mar 22
Utility
Compositions Comprising Enzyme-cleavable Amphetamine Prodrugs and Inhibitors Thereof
9 Jun 22
The embodiments provide Compound AM-9, Amphetamine-arginine-glycine-acetate, or acceptable salts, solvates, and hydrates thereof and Compound AM-10, Amphetamine-arginine-alanine-acetate.
Thomas E. Jenkins, Craig O. Husfeld, Julie D. Seroogy, Jonathan W. Wray
Filed: 4 Mar 20
Utility
Footwear with heel contact member
14 Oct 19
A footwear device is provided having a deformable heel contact member.
Louis F. Polk
Filed: 21 Jun 17
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