6 patents
Utility
Pikfyve Kinase Inhibitors
4 May 23
The present invention relates to compounds useful as inhibitors of phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) as well as their use for treating diseases and disorders associated with PIKfyve.
Martin SMRCINA, Ronghua LI, Anil NAIR, Paul AUGUST, Kirsten BJERGARDE, Jennifer LUDINGTON
Filed: 11 Feb 21
Utility
UNC13A Antisense Oligonucleotides
27 Apr 23
The present invention relates to UNC13A cryptic exon antisense oligonucleotides (ASOs), pharmaceutical compositions containing them, and methods for treating, inhibiting, suppressing, and preventing neurological diseases with them.
Wen-Hsuan Chang, Justin K. Ichida
Filed: 21 Jul 22
Utility
Pikfyve Antisense Oligonucleotides
29 Dec 22
The present invention relates to PIKFYVE antisense oligonucleotides (ASOs), pharmaceutical compositions containing them, and methods for treating, inhibiting, suppressing, and preventing neurological diseases with them.
Wen-Hsuan Chang, Emily Elizabeth Lee
Filed: 22 Jun 22
Utility
Treatment of Viral Infections with Combination of Pikfyve Kinase Inhibitors and TMPRSS-2 Inhibitors
4 Nov 21
The present invention relates to methods of treating viral infections including COVID-19 and compositions with a combination of (i) an inhibitor of phosphatidylinositol-3-phosphate 5-kinase (PIKfyve) and (ii) an inhibitor of transmembrane serine proteinase 2 (TMPRSS-2).
Justin K. Ichida, Matthew Stremlau, Hongyan Zhou
Filed: 3 May 21
Utility
Method for Identifying Effective Treatments Against Neurodegenerative Disorders
4 Feb 21
The present invention relates to systems and methods for reprogramming cells to generate neurons and identifying effective treatments for neurodegenerative disorders using such neurons, as well as systems and methods for treating and developing treatments for one or more neurodegenerative disorders.
Justin K. Ichida, Hongyan Zhou, Wen-Hsuan Chang, Samuel V. Alworth
Filed: 31 Dec 19
Utility
Pikfyve Kinase Inhibitors
24 Jun 20
Martin Smrcina, Ronghua Li, Anil Nair, Paul August, Kirsten Bjergarde
Filed: 27 Aug 18
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