4 patents
Utility
Cancer Cell Modulators
12 Oct 23
Disclosed are cancer cell- and proliferative cell-selective small molecule compounds that modulate certain cancer cell- or proliferative cell-specific metabolic enzymes or receptors, and methods of their use to treat cancer and other proliferative disorders.
Nathaniel Sherden, Shen Yu
Filed: 29 Jan 21
Utility
Modulation of Immune Cells
20 Apr 23
Disclosed are immune cell-selective small molecule IMPDH inhibitor compounds and methods of their synthesis and use to treat proliferative disorders.
Nathaniel SHERDEN, SHEN YU, LUIS CASTILLO-MENENDEZ, ISAAC STONER, BRENT CEZAIRLIYAN
Filed: 29 Jan 21
Utility
Immune Cell Modulators
20 Apr 23
Disclosed are immune cell-selective small molecule compounds that modulate certain immune cell-specific receptors and enzymes, and methods of their synthesis and use to treat proliferative disorders.
Nathaniel Sherden, Shen Yu, Isaac Stoner
Filed: 29 Jan 21
Utility
Pre-Activated Nucleoside IMPDH Inhibitors As Anti-Infective Drugs
18 Nov 21
The present disclosure provides inosine-5′-monophosphate dehydrogenase (IMPDH)-inhibiting nucleoside derivatives having anti-infective activities, and methods of their synthesis and use.
Nathaniel Sherden
Filed: 4 Oct 19
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