416 patents
Page 3 of 21
Utility
Sample Handling Apparatus and Image Registration Methods
2 Nov 23
A method for aligning a sample to an array is provided.
Augusto Manuel Tentori, Hanyoup Kim, Siyuan Xing, Felice Alessio Bava, Rajiv Bharadwaj, Cedric Uytingco, Erica Graziosa
Filed: 17 Sep 21
Utility
Spatial Transcriptomics for Antigen-receptors
26 Oct 23
Provided herein are methods, compositions, and kits for the detection of immune cell clonotypes and immune cell analytes within a biological sample.
Camilla Engblom, Kim Thrane, Jeffrey Mold, Jonas Frisen, Joakim Lundeberg, Qirong Lin
Filed: 10 May 23
Utility
Method for Transposase-mediated Spatial Tagging and Analyzing Genomic Dna In a Biological Sample
26 Oct 23
The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla
Filed: 19 Sep 22
Utility
Methods and Systems for Sample Preparation and Analysis
26 Oct 23
The present disclosure provides methods and systems for sample preparation and/or analysis.
Zahra Kamila BELHOCINE, Josephine Lee, Francesca MESCHI, Luz MONTESCLAROS, Katherine PFEIFFER, Andrew D. PRICE, Jerald SAPIDA, David SUKOVICH, Tobias Daniel WHEELER, Yifeng YIN
Filed: 17 Jan 23
Utility
Spatial Analysis of Dna Methylation
26 Oct 23
Provided herein are methods of identifying a methylation status of an analyte in a biological sample.
Layla Katiraee, Michael Schnall-Levin, Christina Galonska, Marlon Stoeckius
Filed: 18 Apr 23
Utility
Compositions and Methods for Binding an Analyte to a Capture Probe
19 Oct 23
Provided herein are methods and kits for binding of an analyte capture sequence to a capture domain of a capture probe.
Jennifer Chew, Marlon Stoeckius
Filed: 3 May 23
Utility
Methods, Compositions, and Systems for Capturing Analytes from Glioblastoma Samples
19 Oct 23
Provided herein are methods, compositions and systems for identifying spatial gene expression of analytes from glioblastoma derived tissue.
Hardeep Pal Singh, David Sukovich, Seayar Mohabbat, Dongyao Li, Hanyoup Kim, Augusto Manuel Tentori
Filed: 23 Jun 23
Utility
Methods, Compositions, and Systems for Spatial Analysis of Analytes In a Biological Sample
19 Oct 23
Provided herein are methods for capturing a connected probe and/or a capture handle sequence to a capture domain of a capture probe.
Hanyoup Kim, David Sukovich, Layla Katiraee, Augusto Manuel Tentori, Lauren Gutgesell, Janine Hensel, Seayar Mohabbat
Filed: 27 Apr 23
Utility
Spatial Assays with Perturbed Cells
19 Oct 23
This disclosure relates to methods for spatial profiling of analytes present in a biological sample.
Eswar Prasad Ramachandran Iyer
Filed: 23 Jun 23
Utility
Sequencing Methods
19 Oct 23
The invention described herein solves challenges in providing a proficient, rapid and meaningful analysis of sequencing data.
Michael Schnall-Levin, Mirna Jarosz, Serge Saxonov, Kevin Ness, Benjamin Hindson
Filed: 17 May 23
Utility
Methods and Compositions for Multiplex Cell Analysis
12 Oct 23
Provided herein in some aspects are methods, compositions, kits, and systems for performing multiplexed single-cell analysis on an in situ platform, providing alternatives which have a higher cell throughput and/or lower cost per cell compared to current single-cell analysis techniques.
Michael SCHNALL-LEVIN
Filed: 6 Apr 23
Utility
Enhancing Specificity of Analyte Binding
12 Oct 23
Methods for enhancing specificity of an analyte binding moiety or probe oligonucleotide to an analyte are provided herein.
Marlon Stoeckius
Filed: 24 May 23
Utility
Methods and Compositions for Ligation and Sample Analysis
12 Oct 23
The present disclosure relates in some aspects to methods for analyzing a target nucleic acid in a biological sample.
Shankar SHASTRY
Filed: 7 Apr 23
Utility
Generating Capture Probes for Spatial Analysis
12 Oct 23
The present disclosure relates to compositions and methods for generating capture probes on a substrate for identifying the location of analytes in a biological sample.
Yifeng Yin, Michael Schnall-Levin, Eswar Prasad Ramachandran Iyer
Filed: 16 Mar 23
Utility
Methods and Compositions for Stabilizing And/or Compacting Nucleic Acid
12 Oct 23
The present disclosure in some aspects relates to methods and compositions for accurately detecting and quantifying multiple analytes present in a biological sample.
Hong CHEN, Evan R. DAUGHARTHY, Shoshoni DROZ, Milena LAZOVA, Zhao ZHAO
Filed: 2 Aug 22
Utility
Systems with a Gasket and Methods for Analyzing Samples
12 Oct 23
Disclosed herein are systems for receiving a biological sample for analysis and methods for preparing and/or analyzing a biological sample.
Yiran ZHANG, Felice Alessio BAVA, Rhyan Blaine DOCKTER, Rajiv BHARADWAJ
Filed: 7 Apr 23
Utility
Method for Transposase-mediated Spatial Tagging and Analyzing Genomic Dna In a Biological Sample
12 Oct 23
The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes
Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla, Eswar Prasad Ramachandran Iyer, Lucas Frenz, Augusto Manuel Tentori, Rajiv Bharadwaj
Filed: 27 Aug 19
Utility
Methods of Determining a Surgical Margin and Methods of Use Thereof
12 Oct 23
Provided herein are methods of determining a surgical margin and the site and size of a tissue to be resected from a subject, and methods of use thereof.
Smritee Dadhwal
Filed: 14 Jun 23
Utility
Method of Detecting Target Nucleic Acid Molecules
5 Oct 23
The present application provides methods for detecting a nucleic acid molecule involving the use of a signal code sequence which corresponds to said nucleic acid molecule and a plurality of labelled detection probes which yield signals which make up the signal code sequence.
Malte KÜHNEMUND, Toon VERHEYEN
Filed: 22 Nov 22
Utility
Blister Packs and Uses Thereof
5 Oct 23
Systems that include blister packs and methods of use thereof are disclosed.
David MORGAN, Evan DEJARNETTE, Eric EVJE, Yiran ZHANG, Siyuan XING
Filed: 5 Apr 23