20 patents
Utility
Compositions and Methods of Treatment for Severe Hypertriglyceridemia
28 Dec 23
Compositions, methods and therapeutic regimens of mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugates for the treatment of severe hypertriglyceridemia are provided.
Hank Mansbach, Leo Tseng
Filed: 23 Jun 23
Utility
1,4-Substituted Piperidine Derivatives
7 Dec 23
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak, Allison Zulli
Filed: 2 Jun 23
Utility
Liquid Formulations Comprising Mutant FGF-21 Peptide Pegylated Conjugates
26 Oct 23
The present disclosure relates to liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate and prefilled syringe or autoinjector comprising liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate.
Boris SCHWARTSBURD, Shaji JOSEPH
Filed: 6 Feb 23
Utility
1,4-substituted piperidine derivatives
18 Jul 23
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak, Allison L. Zulli
Filed: 5 Nov 20
Utility
Methods for Promoting Weight Loss
23 Mar 23
Therapeutic regimens and uses of mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugates comprising a polyethylene glycol (PEG) moiety attached to a mutant FGF-21 peptide via a glycosyl moiety thereof in the reduction of total body weight, reduction of body fat content, and/or reduction of BMI of the subject in need thereof are provided.
Mordechay ROSENSTOCK, Maya MARGALIT
Filed: 29 Jan 21
Utility
Liquid formulations comprising mutant FGF-21 peptide pegylated conjugates
7 Mar 23
The present disclosure relates to liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate and prefilled syringe or autoinjector comprising liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate.
Boris Schwartsburd, Shaji Joseph
Filed: 10 Mar 22
Utility
Methods of Treatment Using Mutant FGF-21 Peptide Conjugates
29 Sep 22
Therapeutic regimens and uses of mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugates comprising a polyethylene glycol (PEG) moiety attached to a mutant FGF-21 peptide via a glycosyl moiety thereof in the treatment of nonalcoholic steatohepatitis are provided.
Hank MANSBACH, Chih-Ming TSENG
Filed: 16 Jun 22
Utility
Liquid Formulations Comprising Mutant FGF-21 Peptide Pegylated Conjugates
22 Sep 22
The present disclosure relates to liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate and prefilled syringe or autoinjector comprising liquid pharmaceutical compositions comprising mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate.
Boris Schwartsburd, Shaji Joseph
Filed: 10 Mar 22
Utility
Methods of treatment using mutant FGF-21 peptide conjugates
30 Aug 22
Therapeutic regimens and uses of mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugates comprising a polyethylene glycol (PEG) moiety attached to a mutant FGF-21 peptide via a glycosyl moiety thereof in the treatment of nonalcoholic steatohepatitis are provided.
Hank Mansbach, Chih-Ming Tseng
Filed: 28 May 20
Utility
Substituted 4-Benzyl And 4-Benzoyl Piperidine Derivates
17 Mar 22
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak
Filed: 15 Feb 21
Utility
Mutant FGF-21 Peptide Pegylated Conjugates and Uses Thereof
18 Nov 21
The present invention relates to a mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate comprising a PEG moiety attached to a mutant FGF-21 peptide via a glycosyl linker and uses thereof.
Karla K. Kopec, Patrick Mengyuan Liu
Filed: 27 May 21
Utility
Spiropiperidine Derivatives
16 Sep 21
Robert L. Hudkins, David B. Whitman, Craig A. Zificsak, Allison L. Zulli, Melody McWherter
Filed: 25 May 21
Utility
1,4-Substituted Piperidine Derivatives
29 Jul 21
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak, Allison L. Zulli
Filed: 5 Nov 20
Utility
Spiropiperidine derivatives
29 Jun 21
Robert L. Hudkins, David B. Whitman, Craig A. Zificsak, Allison L. Zulli, Melody McWherter
Filed: 14 Dec 17
Utility
Method of Treating of Fibroblast Growth Factor 21 (FGF-21) Deficiency
8 Apr 21
The present invention relates to mutants of Fibroblast Growth Factor (FGF), particularly FGF-20 and FGF-21, which contain newly introduced N-Linked or O-Linked glycosylation site(s).
Shawn DeFrees
Filed: 20 Oct 20
Utility
Substituted 4-benzyl and 4-benzoyl piperidine derivatives
16 Feb 21
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak
Filed: 17 Jun 16
Utility
Method of treating fibroblast growth factor 21 (FGF-21) deficiency
28 Dec 20
The present invention relates to mutants of Fibroblast Growth Factor (FGF), particularly FGF-20 and FGF-21, which contain newly introduced N-linked or O-linked glycosylation site(s).
Shawn DeFrees
Filed: 29 Nov 15
Utility
1,4-substituted piperidine derivatives
30 Nov 20
Nadine C. Becknell, Reddeppa Reddy Dandu, Bruce D. Dorsey, Dimitar B. Gotchev, Robert L. Hudkins, Linda Weinberg, Craig A. Zificsak, Allison L. Zulli
Filed: 24 Jan 19
Utility
Spiropiperidine Derivatives
29 Jan 20
Robert L. HUDKINS, David B. WHITMAN, Craig A. ZIFICSAK, Allison L. ZULLI, Melody MCWHERTER
Filed: 13 Dec 17
Utility
Mutant FGF-21 Peptide Pegylated Conjugates and Uses Thereof
25 Dec 19
The present invention relates to a mutant Fibroblast Growth Factor-21 (FGF-21) peptide conjugate comprising a PEG moiety attached to a mutant FGF-21 peptide via a glycosyl linker and uses thereof.
Karla K. KOPEC, Patrick Mengyuan LIU
Filed: 17 Jul 19
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