19 patents
Utility
Activatable INTERLEUKIN-2 Polypeptides and Methods of Use Thereof
23 Nov 23
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 9 Oct 22
Utility
Separation Moieties and Methods of Use Thereof
31 Aug 23
Provided herein are separation moieties that are suitable for use in conjunction with a variety of therapeutic payloads.
William WINSTON, Luke EVNIN, Vinay BHASKAR, Giselle KNUDSEN, Daniel J. HICKLIN, Cynthia SEIDEL-DUGAN, Jose Andres SALMERON-GARCIA, Heather R. BRODKIN
Filed: 11 May 23
Utility
Activatable Cytokine Polypeptides and Methods of Use Thereof
23 Feb 23
The disclosure features fusion proteins that are conditionally active variants of a cytokine of interest.
William WINSTON, Daniel HICKLIN, Jose Andres SALEMERON-GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 23 Sep 22
Utility
Activatable Cytokine Polypeptides and Methods of Use Thereof
16 Feb 23
The disclosure features fusion proteins that are conditionally active variants of a cytokine of interest.
William WINSTON, Daniel HICKLIN, Jose Andres SALMERON-GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 10 May 22
Utility
Activatable interleukin-2 polypeptides and methods of use thereof
27 Dec 22
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 10 Nov 21
Utility
Activatable Interleukin 12 Polypeptides and Methods of Use Thereof
13 Oct 22
The disclosure features fusion proteins that are conditionally active variants of IL-12.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 11 Apr 22
Utility
Activatable interleukin 12 polypeptides and methods of use thereof
27 Sep 22
The disclosure features fusion proteins that are conditionally active variants of IL-12.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 21 May 20
Utility
Separation Moieties and Methods of Use Thereof
14 Jul 22
Provided herein are separation moieties that are suitable for use in conjunction with a variety of therapeutic payloads.
William WINSTON, Luke EVNIN, Vinay BHASKAR, Giselle KNUDSEN, Daniel J. HICKLIN, Cynthia SEIDEL-DUGAN, Jose Andres SALMERON GARCIA, Heather R. BRODKIN
Filed: 22 Feb 22
Utility
Activatable interleukin-2 polypeptides and methods of use thereof
7 Jun 22
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 21 May 20
Utility
Activatable INTERLEUKIN-2 Polypeptides and Methods of Use Thereof
24 Feb 22
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 10 Nov 21
Utility
Activatable INTERLEUKIN-2 Polypeptides and Methods of Use Thereof
30 Dec 21
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN, Cynthia SEIDEL-DUGAN
Filed: 14 May 21
Utility
Activatable Cytokine Polypeptides and Methods of Use Thereof
6 May 21
The disclosure features fusion proteins that are conditionally active variants of a cytokine of interest.
William WINSTON, Heather BRODKIN, Cynthia SEIDEL-DUGAN, Daniel HICKLIN, Jose Andres SALMERON-GARCIA
Filed: 22 Sep 20
Utility
Separation Moieties and Methods of Use Thereof
22 Apr 21
Provided herein are separation moieties that are suitable for use in conjunction with a variety of therapeutic payloads.
William WINSTON, Luke EVNIN, Vinay BHASKAR, Giselle KNUDSEN, Daniel HICKLIN, Cynthia SEIDEL-DUGAN, Jose Andres SALMERON GARCIA, Heather BRODKIN
Filed: 28 Oct 20
Utility
Activatable Interleukin 12 Polypeptides and Methods of Use Thereof
9 Sep 20
The disclosure features fusion proteins that are conditionally active variants of IL-12.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 20 May 20
Utility
Activatable INTERLEUKIN-2 Polypeptides and Methods of Use Thereof
9 Sep 20
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 20 May 20
Utility
Activatable interleukin 12 polypeptides
29 Jun 20
The disclosure features fusion proteins that are conditionally active variants of IL-12.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 10 Jun 19
Utility
Activatable interleukin-2 polypeptides
29 Jun 20
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William Winston, Daniel Hicklin, Vinay Bhaskar, Luke Evnin, Patrick Baeuerle, Jose Andres Salmeron Garcia, Heather Brodkin, Cynthia Seidel-Dugan
Filed: 10 Jun 19
Utility
Activatable INTERLEUKIN-2 Polypeptides and Methods of Use Thereof
5 Feb 20
The disclosure features fusion proteins that are conditionally active variants of IL-2.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN
Filed: 10 Jun 19
Utility
Activatable Interleukin 12 Polypeptides and Methods of Use Thereof
4 Dec 19
The disclosure features fusion proteins that are conditionally active variants of IL-12.
William WINSTON, Daniel HICKLIN, Vinay BHASKAR, Luke EVNIN, Patrick BAEUERLE, Jose Andres SALMERON GARCIA, Heather BRODKIN
Filed: 10 Jun 19
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