8 patents
Utility
Topical roflumilast formulation having improved delivery and plasma half-life
21 Nov 23
The present invention is directed to methods for improving the therapeutic outcome of treatment with roflumilast.
David W. Osborne
Filed: 1 Mar 23
Utility
Inhibition of crystal growth of roflumilast
24 Oct 23
Roflumilast crystals have been shown to increase in size during storage.
David W. Osborne
Filed: 23 Nov 20
Utility
Laureth-4 containing topical formulations
22 Aug 23
The present invention is a method and composition comprising laureth-4 in topical formulations, wherein the laureth-4 increases the penetration of active ingredients across the skin.
David W. Osborne
Filed: 27 Jul 21
Utility
Topical roflumilast formulation having antifungal properties
25 Jul 23
The present invention is directed to a method of treating a fungal infection comprising administering topically, to a subject in need thereof, an anti-fungal effective amount of roflumilast.
David Reuben Berk, Patrick Eugene Burnett, Saori Kato, David W. Osborne
Filed: 3 Dec 21
Utility
Compositions and methods for deep dermal drug delivery
18 Apr 23
Pharmaceutical compositions for the topical administration of a drug to the pilosebaceous unit and methods for administering the same.
David W. Osborne, Babak N. Tofig
Filed: 16 Nov 21
Utility
Pharmaceutical compositions of roflumilast in aqueous blends of water-miscible, pharmaceutically acceptable solvents
27 Dec 22
The low aqueous solubility of roflumilast in parenteral preparations and topical emulsions, suspensions, gels or solutions can be improved by including a blend of water-miscible solvents in the pharmaceutical composition.
David W. Osborne
Filed: 22 Sep 17
Utility
Topical roflumilast formulation having improved delivery and plasma half life
28 Sep 21
The present invention is directed to methods for improving the therapeutic outcome of treatment with roflumilast.
David W. Osborne, Bhaskar Chaudhuri, Archie W. Thurston, Jr.
Filed: 31 Jan 20
Utility
Inhibition of crystal growth of roflumilast
9 Mar 21
Roflumilast crystals have been shown to increase in size during storage.
David W. Osborne
Filed: 20 Sep 18
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