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MRVI Maravai LifeSciences

APP
Utility
Compositions and Methods for Synthesizing 5'-CAPPED Rnas
2 Dec 21
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form m7Gppp[N2′Ome]n[N]m wherein m7G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.
Richard I. HOGREFE, Alexandre LEBEDEV, Anton P. MCCAFFREY, Dongwon SHIN
Filed: 2 Aug 21
APP
Utility
Compositions and Methods for Synthesizing 5'-CAPPED Rnas
26 Aug 21
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form m7 Gppp[N2′Ome]n[N]m wherein m7G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.
Richard I. HOGREFE, Alexandre LEBEDEV, Anton P. MCCAFFREY, Dongwon SHIN
Filed: 6 Nov 20
APP
Utility
Stock Solution of Retrovirus Like Particles with Method and Kit
27 May 21
The present invention relates to a stock solution (RLP Stock Solution) of mammalian cell-endogenous retrovirus like particles (RLP), a method of preparing a RLP stock solution, a kit containing a RLP stock solution, and a method of quantifying the amount of RLP removed from a solution.
David Cetlin, Arun Dhar
Filed: 4 Feb 21
GRANT
Utility
Immunofluorescence assays
6 Apr 21
Provided herein are immunofluorescence assays that do not use an intensely colored lipophilic dye, and that result in a significant reduction of fluorescence due to aldehyde fixation, collagen, elastin, and/or red blood cells.
Timothy B. Karpishin, Pamela James, Erika Leonard
Filed: 3 May 18
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