3 patents
Utility
Compositions and methods for synthesizing 5'-Capped RNAs
14 Feb 23
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form m7Gppp[N2′Ome]n[N]m wherein m7G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.
Richard I. Hogrefe, Alexandre Lebedev, Anton P. McCaffrey, Dongwon Shin
Filed: 26 May 22
Utility
Compositions and methods for synthesizing 5′-capped RNAs
16 Aug 22
Provided herein are methods and compositions for synthesizing 5′Capped RNAs wherein the initiating capped oligonucleotide primers have the general form m7Gppp[N2′Ome]n[N]m wherein m7G is N7-methylated guanosine or any guanosine analog, N is any natural, modified or unnatural nucleoside, “n” can be any integer from 0 to 4 and “m” can be an integer from 1 to 9.
Richard I. Hogrefe, Alexandre Lebedev, Anton P. McCaffrey, Dongwon Shin
Filed: 2 Aug 21
Utility
Immunofluorescence assays
6 Apr 21
Provided herein are immunofluorescence assays that do not use an intensely colored lipophilic dye, and that result in a significant reduction of fluorescence due to aldehyde fixation, collagen, elastin, and/or red blood cells.
Timothy B. Karpishin, Pamela James, Erika Leonard
Filed: 3 May 18
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