7 patents
Utility
Liver-specific WNT Signal Enhancing Molecules and Uses Thereof
23 Nov 23
The present disclosure provides liver-specific Wnt signal enhancing molecules, and related methods of using these molecules to increase Wnt signaling in liver tissues and treat liver diseases and disorders.
Yang LI, Zhengjian ZHANG, Randall J. BREZSKI, Leonard PRESTA, Thomas LOPEZ, Hui CHEN, Helene BARIBAULT, Wen-Chen YEH, Shengjiang TU
Filed: 2 May 23
Utility
WNT surrogate molecules and uses thereof
3 Oct 23
The present invention provides Wnt pathway agonists and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.
Yang Li, Tom Zhiye Yuan, Aaron Ken Sato, Wen-Chen Yeh, Claudia Yvonne Janda, Tristan William Fowler, Helene Baribault, Kuo-Pao Lai, Liqin Xie, Randall J. Brezski, Chenggang Lu
Filed: 19 Dec 18
Utility
WNT Receptor-specific Compound and Method Relating Thereto
21 Sep 23
The present invention provides compounds which specifically bind to one or more Wnt receptors and methods relating thereto.
Hui CHEN, Sungjin LEE, Yang LI, Wen-Chen YEH
Filed: 30 Dec 22
Utility
Anti-LRP5/6 antibodies and methods of use
5 Sep 23
The present invention provides anti-LRP5/6 monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for treating diseases and disorders associated with Wnt pathway signaling.
Yang Li, Tom Zhiye Yuan, Aaron Ken Sato, Wen-Chen Yeh, Parthasarathy Sampathkumar
Filed: 19 Dec 18
Utility
WNT Super Agonists
4 May 23
The present invention provides multispecific multivalent antigen binding molecules that can function as WNT agonist, WNT enhancer, and WNT super agonist molecules by binding and activating at least one or two WNT receptors and a WNT enhancer.
Yang LI
Filed: 24 Feb 21
Utility
Monospecific Anti-frizzled Antibodies and Methods of Use
1 Sep 22
The present invention provides anti-Fzd monoclonal antibodies and related compositions, which may be used in any of a variety of therapeutic methods for the treatment of diseases.
Yang LI, Thomas Steven LOPEZ, I-Chieh WANG, Parthasarathy SAMPATHKUMAR
Filed: 2 Jul 20
Utility
Modulation of WNT Signaling In Auditory Disorders
9 Jun 22
Methods of treating auditory disorders with modulators of the WNT signaling pathway are disclosed.
Sungjin LEE, Yang LI, Wen-Chen YEH
Filed: 1 Apr 20
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