2 patents
Utility
Raf Inhibitor for Treating Low Grade Glioma
9 Nov 23
Described herein are methods and compositions for treating gliomas such as pediatric low grade glioma.
Karen D. WRIGHT, Daphne Adele HAAS-KOGAN, Samuel c. BLACKMAN
Filed: 5 Nov 21
Utility
Solid Dispersion of Pan-raf Kinase Inhibitor
22 Dec 22
The present disclosure provides a pharmaceutical composition comprising a solid dispersion having a mass median diameter of about 75 μm to about 400 μm, and one or more pharmaceutically acceptable excipients, wherein the solid dispersion comprises (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide, or a pharmaceutically acceptable salt thereof, and a vinylpyrrolidone-vinyl acetate copolymer.
Yuki KODONO, Yasushi SHONO, Hirohisa TAKEUCHI
Filed: 25 May 22
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