3525 patents
Utility
3D Electrode Design for a High Specific-capacity Al-graphite Dual-ion Battery
18 Jan 24
An aluminum electrode can include gel polymer as the binder, which can be combined with a carbon electrode to form a dual-ion battery.
Yang Shao-Horn, Yun Guang Zhu
Filed: 12 May 23
Utility
Sulfonimide Salts for Battery Applications
18 Jan 24
A class of sulfonimide salts for solid-state electrolytes can be synthesized based on successive SNAr reactions of fluorinated phenyl sulfonimides: Fluorinated Aryl Sulfonimide Tags (FAST).
Jeremiah Allen Johnson, Yang Shao-Horn, Robinson Anandakathir, Mao Chen, Shuting Feng, Livia Giordano, Mingjun Huang, Wenxu Zhang
Filed: 26 Jan 23
Utility
Medical Devices and Implements with Liquid-impregnated Surfaces
18 Jan 24
Described herein are medical devices and medical implements with high lubricity to flesh (or biological fluid) and/or inhibited nucleation on its surface.
J. David Smith, Rajeev Dhiman, Adam T. Paxson, Christopher J. Love, Brian R. Solomon, Kripa K. Varanasi
Filed: 15 May 23
Utility
Gravity Based Drug Delivery Device
18 Jan 24
A drug delivery device may be configured to delivery an active pharmaceutical ingredient (API) to a subject via the subject's oral-gastrointestinal (GI) tract.
Carlo Giovanni Traverso, Niclas Roxhed, Siheng You, Graham Arrick, Torben Sebastian Last
Filed: 20 Oct 21
Utility
Novel CAS13B Orthologues Crispr Enzymes and Systems
18 Jan 24
The invention provides for systems, methods, and compositions for targeting nucleic acids.
David Benjamin Turitz Cox, Neena Pyzocha, Feng Zhang
Filed: 10 Jul 23
Utility
a Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression
18 Jan 24
Provided herein are feedback controller circuits and cell state classifiers for tunable phosphorylation-based transcriptional regulation of gene expression in cells based on intracellular miRNA profiles and degradation by small molecules.
Ross D. Jones, Yili Qian, Domitilla Del Vecchio, Ron Weiss
Filed: 2 Dec 21
Utility
Co-packaging to Mitigate Intermolecular Recombination
18 Jan 24
The subject matter disclosed herein is generally directed to methods and compositions for stable transduction of target cells with libraries of genetic elements.
David Feldman, Avtar Singh, Paul Blainey
Filed: 19 Dec 22
Utility
Mixture Deconvolution Method for Identifying Dna Profiles
18 Jan 24
This patent application relates generally to mixture deconvolution systems and methods for identifying DNA profiles.
Philip Fremont-Smith, Chelsea Lynn Lennartz, Natalie Damaso
Filed: 15 May 23
Utility
Novel Crispr Enzymes and Systems
18 Jan 24
Embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the CRISPR complex to the binding site and/or alters editing preference as compared to wild type.
Feng Zhang, David Arthur Scott, Winston Xia Yan, Sourav Choudhury, Mattias Heidenreich
Filed: 30 Jun 23
Utility
Transcriptomics with Electrophysiological Recording
18 Jan 24
Disclosed herein are methods and systems for correlating continuous physiological processes (e.g., electrophysiological activity) and biomolecular processes (e.g., gene expression) in cells within a tissue.
Xiao Wang, Jia Liu
Filed: 27 Oct 21
Utility
Synthetic 5' UTR sequences, and high-throughput engineering and screening thereof
16 Jan 24
Disclosed herein are novel 5′ UTR sequences that can be used to control gene expression in various contexts.
Timothy Kuan-Ta Lu, Manolis Kellis, Jicong Cao, Eva Maria Novoa Pardo, Zhizhuo Zhang
Filed: 14 Jun 19
Utility
System and method for an optical blood flow measurement
16 Jan 24
An apparatus, including: a probe to interface with a surface of a tissue; a light source optically coupled to the probe, the light source directing light of at least 1000 nm into the tissue; a detector optically coupled to the probe, the detector to detect light based on scattering of light from the light source in the tissue, and the detector having a light sensitivity in a range of at least 1000 nm; a processor coupled to the detector, the processor to: receive a signal from the detector corresponding to the detected light from the light source, and determine a blood flow measurement from the region of interest using diffuse correlation spectroscopy based on the signal.
Maria Angela Franceschini, Stefan Carp, Davide Tamborini, David Boas, Bruce Rosen, Megan Blackwell, Oleg Shatrovoy
Filed: 18 Feb 19
Utility
SARS-CoV-2 antigens and uses thereof
16 Jan 24
The present disclosure relates to, inter alia, variants of the receptor binding domain of a coronavirus (e.g., SARS-CoV-2) having increased immunogenicity and reduced aggregation, and the use of the RBD variants in methods for preventing infection of the coronavirus.
J. Christopher Love, Sergio Andre Rodriguez Aponte, Neil Chandra Dalvie
Filed: 28 Oct 21
Utility
Porous medium with adjustable fluid permeability and associated systems and methods
16 Jan 24
The present disclosure is related to porous media with adjustable fluid permeabilities and related systems and methods.
Yayuan Liu, Trevor Alan Hatton
Filed: 30 Mar 21
Utility
Additive manufacturing of composite powders
16 Jan 24
Compositions and methods of making compositions for additive manufacturing of composite powders including metal ceramic alloyed material is described.
Ethan Parsons
Filed: 5 Nov 21
Utility
Swellable and structurally homogenous hydrogels and methods of use thereof
16 Jan 24
The invention encompasses hydrogels, monomer precursors of the hydrogels, methods for the preparation thereof, and methods of use therefor.
Ruixuan Gao, Linyi Gao, Chih-Chieh Yu, Edward Stuart Boyden
Filed: 5 Feb 19
Utility
Nanostructures for the assembly of materials
16 Jan 24
Nanostructures and associated compositions, systems, and methods are provided.
Robert J. Macfarlane, Jianyuan Zhang, Peter Jeffries Santos, Paul Anthony Gabrys
Filed: 5 Aug 21
Utility
Electrically conductive firebrick system
16 Jan 24
A thermal energy storage system includes a firebrick checkerwork and an electrode.
Charles Forsberg, Daniel C. Stack
Filed: 31 Aug 21
Utility
Sole Structure of a Shoe
11 Jan 24
An article of footwear includes an upper and a sole structure.
Matthias HARTMANN, Reinhold SUSSMANN, Federico CASALEGNO, Hunmin KOH, Yihyun LIM, Yasaman TAHOUNI, Will WALKER
Filed: 19 Sep 23
Utility
Daughterless Male Mammals for Non-human Population Suppression
11 Jan 24
The invention relates, in part, to methods of preparing male organisms of a species that include engineering the male organisms in a manner that eliminates post-embryonic viability of the female offspring and female descendants of the engineered male organisms.
Kevin Michael ESVELT
Filed: 8 Oct 20