451 patents
Page 7 of 23
Utility
CGRP Antigonists Useful As Tracer Compounds for Positron Emission Tomography
30 Mar 23
Mark Donald CHAPPELL, Miles Goodman SIEGEL
Filed: 4 Dec 20
Utility
SSTR4 Agonist Salts
30 Mar 23
The present invention relates to specific salts of (1S,5R)-(1α,5α,6α)-N-[1,1-dimethyl-2-[(3-methyl-2-pyridyl)oxy]ethyl]-3-azabicyclo[3.1.0]hexane-6-carboxamide, to pharmaceutical compositions comprising said salts, to methods of using said salts to treat physiological disorders, and to intermediates useful in the synthesis of the salts.
David Andrew COATES, David Michael REMICK
Filed: 14 Sep 22
Utility
Dose detection with piezoelectric sensing for a medication delivery device
28 Mar 23
The present disclosure relates to a medication delivery device having a dose detection system and an associated control system configured to determine an amount of medication delivered from the medication delivery device based on the sensing of relative rotation within the medication delivery device.
Joseph Edward Katuin, Sean Matthew Pszenny
Filed: 22 Aug 18
Utility
Compounds useful for inhibiting RET kinase
28 Mar 23
Erin D. Anderson, Steven W. Andrews, Kevin R. Condroski, Thomas C. Irvin, Gabrielle R. Kolakowski, Manoj Kumar, Elizabeth A. McFaddin, Megan McKenney, Michael J. Munchhof, Michael B. Welch
Filed: 23 Apr 21
Utility
Therapeutic Uses of Dulaglutide
23 Mar 23
The present invention relates to methods for treating, preventing or delaying disorders relating to cognition, such as cognitive decline, cognitive impairment or dementia in a patient.
Hertzel Chaim GERSTEIN
Filed: 22 Jan 21
Design
Display screen with a graphical user interface
21 Mar 23
Korey Allen Clements
Filed: 13 May 21
Utility
Gripping Attachment for a Bottle
16 Mar 23
A gripping attachment (10) is disclosed which facilitates the handling of a medication bottle (12).
Tonya Lee Chalfant, Carrie Jannean Page, Tony Y. Zhang, Robert Louis Ternik, Matthew Scott Thomas, Jacob Luisi, Michael P. Squillace
Filed: 23 Nov 22
Utility
Methods and Systems for Generating Behavioral Insights Using Survey Instruments and Diabetes Treatment Information
9 Mar 23
A computerized method and system is provided for generating and presenting to a user behavioral insights impacting health outcomes for a person with diabetes.
Rhett Guy ALDEN, Stephanie Smith EDWARDS, Lawrence FISHER, Jennal Lynn JOHNSON, Danielle Marie-Hessler JONES, William Howard POLONSKY, Howard Allan WOLPERT
Filed: 17 Feb 21
Utility
Method for Treating IDH1 Inhibitor-resistant Subjects
9 Mar 23
Nathan Arthur BROOKS, Raymond GILMOUR
Filed: 22 Mar 21
Utility
Solid Forms of 7-[[(1S)-1-[4-[(1S)-2-CYCLOPROPYL-1-(4-PROP-2-ENOYLPIPERAZIN-1-YL)ETHYL]PHENYL]ETHYL]AMINO]-1-ETHYL-4H-PYRIMIDO[4,5-D][1,3]OXAZIN-2-ONE
2 Mar 23
Solid forms including 7-[[(1S)-1-[4-[(1S)-2-cyclopropyl-1-(4-prop-2-enoylpiperazin-1-yl)ethyl]phenyl]ethyl]amino]-1-ethyl-4H-pyrimido[4,5-d][1,3]oxazin-2-one and a dihydroxybenzoic acid selected from 2,5-dihydroxybenzoic acid, 2,4-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid are provided, as well as pharmaceutical compositions including the solid forms, methods for using the solid forms in treating cancer patients, and methods of making the solid forms.
David Andrew COATES, Yizheng CAO
Filed: 12 Aug 22
Utility
Human INTERLEUKIN-4 Receptor Alpha Antibodies
2 Mar 23
The present disclosure relates to antibodies that specifically bind human IL-4Rα, compositions comprising such IL-4Rα antibodies, and methods of using such IL-4Rα antibodies.
Shane Krummen ATWELL, Yiqing FENG, Maya Rachel KARTA, Donmienne LEUNG, Songqing NA, Diana Isabel RUIZ, David John STOKELL, Laura Anne Pelletier
Filed: 5 Aug 22
Utility
Compounds and methods targeting interleukin-19
28 Feb 23
The present invention provides compounds and methods targeting human interleukin-19, including therapeutic antibodies, pharmaceutical compositions and diagnostic applications useful in the field of immune-mediated diseases including psoriasis, atopic dermatitis, psoriatic arthritis, bronchial asthma and diabetic nephropathy.
Richard Earl Higgs, Jr., Robert John Konrad, Brian Jeffrey Nickoloff, Robert William Siegel, II
Filed: 17 Jun 20
Utility
ANTI-IL-1-BETA Antibodies
23 Feb 23
The present disclosure provides human engineered IL-1 beta antibodies, cells and vectors comprising DNA encoding the same, and methods for producing the antibodies.
Wendy Loza HOBBS, Andrew Dixon SKORA
Filed: 19 Jan 21
Utility
Drug Container Systems Including Lock-out Mechanisms
16 Feb 23
A drug delivery system includes a drug delivery device that carries and delivers a drug.
Jaime Ray ARNETT
Filed: 29 Jan 21
Utility
Methods of using and compositions containing dulaglutide
14 Feb 23
The present invention relates to methods of using new doses of dulaglutide and compositions containing such higher doses of dulaglutide.
David Andrew Cox, Zvonko Milicevic, Lai San Tham, David Bradley Woodward
Filed: 13 Nov 18
Utility
Capsule for Gastrointestinal Sampling
2 Feb 23
Passive devices for non-invasive gastrointestinal (GI) sampling are disclosed.
Sina NEJATI, Rahim RAHIMI, Mohit Singh VERMA, Jose Fernando WAIMIN ALMENDARES, Jiangshan WANG
Filed: 16 Dec 20
Utility
Combination therapy with Notch and PI3K/mTOR inhibitors for use in treating cancer
31 Jan 23
Medicaments for use in treating T-cell acute lymphoblastic leukemia, acute lymphoblastic leukemia, acute myelogenous leukemia, chronic myelogenous leukemia, breast cancer, ovarian cancer, melanoma, lung cancer, pancreatic cancer, glioblastoma, sarcoma, desmoid tumors, adenoid cystic carcinoma, colorectal cancer, head and neck cancer, cervical cancer, prostate cancer, liver cancer, or skin cancer in a patient comprising combination therapy with 4,4,4-trifluoro-N-[(1S)-2-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]butanamide, or a pharmaceutically acceptable salt or hydrate thereof, and 8-[5-(1-hydroxy-1-methylethyl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one, or a pharmaceutically acceptable salt thereof.
Bharvin Kumar Patel, Michele C. Smith
Filed: 5 Apr 17
Utility
Novel Rna Therapeutics and Uses Thereof
26 Jan 23
The present disclosure relates to novel RNAi agents designed to decrease the expression of ANGPTL8 in the liver, where the RNAi agents comprise delivery moieties conjugated to oligonucleotides optionally via a linker.
Rebecca Ruth MILES, Jibo WANG, Melissa Ann BELLINGER, Thomas Patrick BEYER, Christine Chih-Tao CHENG, MariJean EGGEN, Gregory Lawrence LACKNER
Filed: 22 Jun 22
Utility
Nasal Delivery Device
26 Jan 23
The present disclosure provides a nasal delivery device with a device body that includes a trigger end and an outlet end.
Jaime Ray ARNETT
Filed: 7 May 21
Utility
Medication Delivery Device
19 Jan 23
The present disclosure relates to a dose detection system for use in combination with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery.
Roy Howard BYERLY, Collin Hunter GRIMES, Jeffrey Manfred GUNNARSSON, Chenrong MENG, Andre Rafael MINOLI, Mariano MUMPOWER, Brian Gregory MURPHY, Aaron Samuel PEARL, Abbie Lynn SHOEMAKER, Samuel Robert ZSCHACK
Filed: 19 Sep 22