120 patents
Page 6 of 6
Utility
Method of Actuation of an Alternating Tangential Flow Diaphragm Pump
2 Dec 20
A control unit includes a first connector configured to connect a proportional pressure regulator to a positive pressure supply and a second connector configured to connect the proportional pressure regulator to a negative pressure supply.
Rudolf Pavlik
Filed: 21 Jun 20
Utility
Tangential Flow Depth Filtration Systems and Methods of Filtration Using Same
18 Nov 20
The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Michael Bransby, Derek Carroll
Filed: 4 Aug 20
Utility
Slope spectroscopy standards
9 Nov 20
The present invention relates generally to a slope spectroscopy standards and methods of making slope spectroscopy standards, specifically standards and methods of developing standards specifically for variable pathlength (slope) measurements.
Mark Salerno, I-Tsung Shih, Craig Harrison
Filed: 18 Jun 19
Utility
Method for Proliferation of Cells Within a Bioreactor Using a Disposable Pumphead and Filter Assembly
14 Oct 20
A method for promoting biological activity uses a filter system to increase cell production of a fed batch bioreactor.
David Serway
Filed: 25 Jun 20
Utility
Plunger pumping arrangement for a hollow fiber filter
12 Oct 20
A fluid filtration assembly includes a filter housing having a first end for fluid connection with a fluid storage vessel.
Rudolf Pavlik
Filed: 27 Dec 17
Utility
Dual pumping arrangement for a hollow fiber filter
5 Oct 20
A fluid filtration assembly includes a filter housing having first and second ends and a connector for fluid communication with a fluid storage vessel.
Rudolf Pavlik
Filed: 27 Dec 17
Utility
Method of actuation of an alternating tangential flow diaphragm pump
14 Sep 20
A control unit includes a first connector configured to connect a proportional pressure regulator to a positive pressure supply and a second connector configured to connect the proportional pressure regulator to a negative pressure supply.
Rudolf Pavlik
Filed: 7 Feb 18
Utility
Tangential flow depth filtration systems and methods of filtration using same
7 Sep 20
The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Michael Bransby, Derek Carroll
Filed: 18 Nov 19
Utility
FC Binding Proteins with Cysteine In the C-terminal Helical Region
29 Jul 20
The present invention relates to Fc binding proteins comprising one or more domains with Cysteine in the C-terminal helical region.
Erik Fiedler, Ulrich Haupts
Filed: 5 Aug 18
Utility
Method for proliferation of cells within a bioreactor using a disposable pumphead and filter assembly
13 Jul 20
A method for promoting biological activity uses a filter system to increase cell production of a fed batch bioreactor.
David Serway
Filed: 10 Apr 16
Utility
Filter for Mammalian Cell Culture Perfusion and Clarification with Hydrophobic Hollow Fiber
1 Jul 20
This disclosure relates to the use of a hydrophobic hollow fiber filter for the filtration of cell cultures and other biological perfusions, due to its resistance to fouling, as well as the ability to filter solutions with a high solid content.
MICHAEL BRANSBY, DEREK CARROLL, PHILIP YUEN
Filed: 29 Dec 19
Utility
Single Use Aseptic Tangential Flow Filtration Systems and Methods
3 Jun 20
Cassettes for tangential flow filtration (TFF) are disclosed which reduce assembly and disassembly required for aseptic filtration.
Mark A. Perreault, John F. Connors, JR., Paul C. Lowell
Filed: 26 Nov 19
Utility
Packed Incompressible Chromatography Resins and Methods of Making the Same
29 Apr 20
This disclosure provides chromatography columns that are packed with incompressible media such as ceramic hydroxyapatite particles, which exhibit high separation performance that is robust to transportation and multiple uses.
James Ronald Peyser, Alan Kit Ho Chan
Filed: 30 Oct 19
Utility
Devices, Systems, and Methods for a Reducer with an Integrated Seal
29 Apr 20
The present disclosure is related to bioprocessing devices, systems, and methods, and particularly to sanitary connections for bioprocessing.
Derek Carroll, Bao Le
Filed: 28 Oct 19
Utility
Sterilizing chromatography columns
6 Apr 20
If one sterilizes pre-packed, plastic chromatography columns with an appropriate level of gamma irradiation, the resulting sterile chromatography columns maintain sufficient packing media function and maintain column mechanical properties and pressure ratings.
James Ronald Peyser, Dana Cristina Pentia
Filed: 15 Jan 15
Utility
Tangential Flow Depth Filtration Systems and Methods of Filtration Using Same
11 Mar 20
The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Michael Bransby, Derek Carroll
Filed: 18 Nov 19
Utility
Tangential flow depth filtration systems and methods of filtration using same
20 Jan 20
The present disclosure relates to hollow fiber tangential flow filters, including hollow fiber tangential flow depth filters, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same.
Michael Bransby, Derek Carroll
Filed: 7 Mar 19
Utility
Methods, Devices and Systems for 3-STAGE Filtration
6 Nov 19
The present disclosure pertains to filtration methods comprising: passing a first fluid that comprises cells, cell debris and targeted product produced by the cells through a first filter thereby separating the first fluid into a first retentate comprising cells and a first permeate comprising targeted product and cell debris; combining resin beads having affinity for targeted product with the first permeate to form a second fluid containing resin beads with bound target product and cell debris; passing the second fluid through a second filter thereby separating the second fluid into a second retentate comprising resin beads with bound target product and a second permeate comprising cell debris; combining an elution buffer with the second retentate to form a third fluid that comprises a mixture of resin beads and unbound targeted product; and passing the third fluid through a third filter thereby separating resin beads from targeted product.
Michael Bransby
Filed: 6 May 18
Utility
Device and Draping Method for Facilitating Introduction of a Non-sterile Container into a Sterile Environment
2 Oct 19
An improved device for enabling a non-sterile container of liquid, such as, for example, a bottle to be introduced into a sterile environment.
William Woods, Michelle Fleming
Filed: 28 Mar 18
Utility
Alkaline Stable Fc-binding Proteins for Affinity Chromatography
2 Oct 19
The present invention relates to Fc binding proteins comprising one or more Fc binding domains wherein at least one domain comprises of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-6 or 21.
Paul Knick, Erik Fiedler, Ulrich Haupts, Maren Meysing
Filed: 6 Aug 17