27 patents
Utility
Compositions and Methods for Embryonic Stem Cell Expansion
5 Oct 23
Provided herein are methods and compositions for expansion of human embryonic stem with suspendable expansion complexes including microcarriers.
Lilach ALON, Rami SKALITER, Ravid TIKOTZKI, Dana HAYOUN NEEMAN, Ofer WISER
Filed: 10 Aug 21
Utility
a Universal Adoptive Immunotherapy Approach to Treat COVID-19 and Future Emerging Infectious Diseases
6 Jul 23
Provided herein are methods and compositions for engineering antigen-presenting cells (APCs), such as dendritic cells (DCs), macrophages, and B-Cells, that are modified to express viral antigens.
Francois BINETTE, Brian M. CULLEY, Rami SKALITER
Filed: 2 Apr 21
Utility
MHC Restricted Immunogenic Telomerase Reverse Transcriptase -Specific Peptides, Their Complex Conjugates, and Methods of Using the Same
4 May 23
The present disclosure provides immunogenic telomerase reverse transcriptase-derived peptide compositions and methods of their use.
Debasish SEN, Kevin P. NISHIMOTO, Casey C. CASE, Jane S. LEBKOWSKI
Filed: 16 Apr 21
Utility
Retinal Pigment Epithelium Cell Compositions
20 Apr 23
Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries.
Nir Netzer, Ofer Wiser, Bat Shahaf, Orit Gamburg, Lior Rosenberg Belmaker, Dana Hayoun Neeman, Osnat Bohana Kashtan
Filed: 14 Dec 22
Utility
Methods and Compositions for Treating Retinal Diseases and Conditions
23 Mar 23
Provided herein are methods, compositions of matter, and devices for treating diseases and illnesses of the eye, including retinal conditions such as macular degeneration.
Francois Binette, Gary Hogge, Rami Skaliter, Avi Ben Shabat, Jordi Monés, Eyal Banin, Tina Guanting Qiu
Filed: 23 Nov 22
Utility
Assessing Retinal Pigment Epithelial Cell Populations
16 Feb 23
A method of qualifying whether a cell population is a suitable therapeutic for treating an eye condition is disclosed.
Osnat Bohana-Kashtan, Lior Ann Rosenberg Belmaker, Ofer Wiser
Filed: 8 Aug 22
Utility
Methods of Treating Retinal Diseases
26 Jan 23
A method of treating a subject with dry-form age-related macular degeneration (AMD) is disclosed.
Eyal Banin, Benjamin Eithan Reubinoff, Osnat Bohana-Kashtan, Nir Netzer, Charles Sherard Irving
Filed: 13 Sep 22
Utility
Retinal Pigment Epithelium Cell Compositions
29 Dec 22
Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries.
Nir Netzer, Ofer Wiser, Bat Shahaf, Orit Gamburg, Lior Rosenberg Belmaker, Dana Hayoun Neeman, Osnat Bohana Kashtan
Filed: 23 Aug 22
Utility
Compositions and Methods for the Treatment of Retinal Degeneration
10 Nov 22
Presented herein are compositions and methods for generating stem cell derived retinal tissue and isolated retinal progenitor cells for use in the treatment of retinal degenerative diseases and disorders.
Igor NASONKIN, Ratnesh SINGH, Francois BINETTE
Filed: 28 Apr 20
Utility
Methods for Differentiating Pluripotent Stem Cells In Dynamic Suspension Culture
25 Aug 22
Methods for differentiating pluripotent stem cells to neuroectoderm in dynamic suspension culture using small molecule or protein inhibitors of TGFβ/Activin/Nodal signaling and BMP signaling are provided.
Rekha R. Nair, Stephanie Kayser, Abhirath S. PARIKH, Uzma Shoukat-Mumtaz, Erik Michael Whiteley, Nathan C. Manley, Craig R. Halberstadt
Filed: 19 Sep 19
Utility
Rpe Cell Populations and Methods of Generating Same
2 Jun 22
A population of human polygonal RPE cells is disclosed.
Osnat Bohana-Kashtan, Lior Ann Rosenberg Belmaker, Ofer Wiser
Filed: 8 Dec 21
Utility
Rpe Cell Populations and Methods of Generating Same
2 Jun 22
A population of human polygonal RPE cells is disclosed.
Osnat Bohana-Kashtan, Lior Ann Rosenberg Belmaker, Ofer Wiser
Filed: 16 Dec 21
Utility
Methods for Measuring Therapeutic Effects of Retinal Disease Therapies
2 Jun 22
Described herein are compositions and methods for treating retinal diseases or disorders using RPE cells.
Oscar Cuzzani, Francois Binette, Gary Hogge
Filed: 9 Dec 21
Utility
Retinal Pigment Epithelium Cell Compositions
31 Mar 22
Presented herein are ready to administer (RTA) retinal pigment epithelium (RPE) cell therapy compositions for the treatment of retinal degenerative diseases and injuries.
Nir NETZER, Ofer WISER, Bat SHAHAF, Orit GAMBURG, Lior ROSENBERG BELMAKER, Dana HAYOUN NEEMAN, Osnat BOHANA KASHTAN
Filed: 10 Dec 21
Utility
Preparation of Retinal Pigment Epithelium Cells
16 Dec 21
A method of generating retinal pigment epithelium cells is disclosed.
Osnat Bohana-Kashtan, Ofer Wiser
Filed: 22 Jun 21
Utility
Rpe Cell Populations and Methods of Generating Same
28 Oct 21
A population of human polygonal RPE cells is disclosed.
Osnat Bohana-Kashtan, Lior Ann Rosenberg Belmaker, Ofer Wiser
Filed: 18 May 21
Utility
Preparation of photoreceptors for the treatment of retinal diseases
17 Aug 21
A method of generating photoreceptors is disclosed.
Osnat Bohana-Kashtan
Filed: 4 Aug 16
Utility
Preparation of retinal pigment epithelium cells
20 Jul 21
A method of generating retinal pigment epithelium cells is disclosed.
Osnat Bohana-Kashtan, Ofer Wiser
Filed: 4 Aug 16
Utility
Methods of selecting retinal pigmented epithelial cells
15 Jun 21
Benjamin Eithan Reubinoff, Nurit Yachimovich-Cohen, Limor Matzrafi
Filed: 28 Mar 17
Utility
Pluripotent Stem Cell-Derived 3D Retinal Tissue and Uses Thereof
27 May 21
Pluripotent stem cell-derived 3D retinal organoid compositions and methods of making using the same are disclosed.
Igor Olegovich Nasonkin, Ratnesh Singh, Michael D. West, Hal Sterberg, David LAROCCA
Filed: 4 Apr 17