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LGND Ligand Pharmaceuticals

GRANT
Utility
Heterocycle amines and uses thereof
30 Nov 21
Compounds and methods in the fields of chemistry and medicine are disclosed.
Koc-Kan Ho, David Diller, Jeffrey J. Letourneau, Brian F. McGuinness, Andrew G. Cole, David Rosen, Cornelis A. van Oeveren, Jason C. Pickens, Lin Zhi, Yixing Shen, Bijan Pedram
Filed: 7 Jan 20
GRANT
Utility
Multi-stage sample recovery system
26 Oct 21
Multi-stage sample-recovery systems, including automated 2-stage and 3-stage sample-recovery systems, are provided.
Bob Chen
Filed: 22 Dec 17
APP
Utility
Compositions and Methods for Inhibiting Endogenous Immunoglobulin Genes and Producing Transgenic Human Idiotype Antibodies
19 Aug 21
The invention relates to transgenic animals lacking endogenous Ig and capable of producing transgenic antibodies, as well as methods of making the same.
Roland BUELOW
Filed: 22 Dec 20
GRANT
Utility
Methods and systems for screening using microcapillary arrays
10 Aug 21
High-throughput methods for screening large populations of variant proteins are provided.
Jennifer R. Cochran, Bob Chen, Spencer Caleb Alford
Filed: 12 Dec 16
APP
Utility
a Monoclonal Antibody Against Human 4-1BB, Method for Preparing the Same, and Use Thereof
29 Jul 21
Provided are novel fully human monoclonal antibodies that bind to human 4-1BB.
Yong ZHENG, Jingjing LIU, Jing LI
Filed: 10 Apr 19
APP
Utility
Glucagon Receptor Antagonists
29 Apr 21
Provided herein are solid state forms of compounds, including enantiomerically pure forms thereof, and pharmaceutically acceptable salts or co-crystals and prodrugs thereof which have glucagon receptor antagonist or inverse agonist activity.
Lin Zhi, Ian Henderson, Joseph Kaloko, Martin Osterhout
Filed: 13 Feb 19
GRANT
Utility
Method for analysis using X-ray fluorescence
16 Mar 21
The present invention is a method to quantify biomarkers.
Lori J. Peterson, Camaron A. Mortillaro, Benjamin P. Warner, Nathan H. Zahler, Pratima Bharti, Chang-Tai Hsieh, Emilia A. Solomon
Filed: 18 Sep 19
APP
Utility
Methods and Compositions Associated with the Granulocyte Colony-stimulating Factor Receptor
18 Feb 21
Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR).
Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
Filed: 10 Jul 20
APP
Utility
Imidazo-fused Heterocycles and Uses Thereof
11 Feb 21
Compounds and methods in the fields of chemistry and medicine are disclosed.
Lin Zhi
Filed: 15 Oct 20
GRANT
Utility
1H-pyrrolo [2,3-b] pyridine derivatives and their use as kinase inhibitors
12 Jan 21
Stephen Stokes, Christopher John Graham, Stuart Christopher Ray, Emma Jayne Stefaniak
Filed: 15 Jun 18
GRANT
Utility
Methods and compositions for modulating hormone levels
28 Dec 20
Provided herein are compositions and methods for the treatment of androgen and estrogen receptors mediated conditions.
Lin Zhi
Filed: 15 Sep 19
GRANT
Utility
Triazolo[4,5-d] pyramidine derivatives and their use as purine receptor antagonists
28 Dec 20
Samantha Jane Bamford, Roger John Gillespie, Richard Simon Todd
Filed: 1 Dec 19
APP
Utility
Selective Androgen Receptor Modulators (Sarms) and Uses Thereof
18 Nov 20
Provided herein are compounds that bind to androgen receptors and/or modulate activity of androgen receptors.
Lin Zhi
Filed: 2 Aug 20
APP
Utility
Acetal Compounds and Therapeutic Uses Thereof
28 Oct 20
Disclosed herein are acetal and cyclic acetal compounds, compositions, their preparation, and their uses.
Lin Zhi
Filed: 7 Jan 19
GRANT
Utility
Imidazo-fused heterocycles and uses thereof
19 Oct 20
Compounds and methods in the fields of chemistry and medicine are disclosed.
Lin Zhi
Filed: 14 Mar 16
GRANT
Utility
SIRP-gamma polypeptide compositions and methods of use
14 Sep 20
Provided herein are SIRP-gamma, SIRP-beta or SIRP-beta2 decoy polypeptides for immunotherapy and/or treatment of cancer, anemia, transplant, asthma, allergy, auto-immune disease, and viral infection.
Aaron Michael Ring, Roy Louis Maute, Andrew Curtis Kruse, Aashish Manglik, Kenneth S. Lin
Filed: 14 Nov 17
APP
Utility
Sirp Polypeptide Compositions and Methods of Use
26 Aug 20
Provided herein are SIRP-gamma, SIRP-beta or SIRP-beta2 decoy polypeptides for immunotherapy and/or treatment of cancer, anemia, transplant, asthma, allergy, auto-immune disease, and viral infection.
Aaron Michael RING, Roy Louis MAUTE, Andrew Curtis KRUSE, Aashish MANGLIK, Kenneth S. LIN
Filed: 3 May 20
GRANT
Utility
Methods and compositions associated with the granulocyte colony-stimulating factor receptor
10 Aug 20
Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR).
Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
Filed: 9 Sep 18
GRANT
Utility
Selective androgen receptor modulators (SARMs) and uses thereof
3 Aug 20
Lin Zhi
Filed: 30 Sep 18
APP
Utility
Heterocycle Amines and Uses Thereof
8 Jul 20
Compounds and methods in the fields of chemistry and medicine are disclosed.
Koc-Kan Ho, David Diller, Jeffrey J. Letourneau, Brian F. McGuinness, Andrew G. Cole, David Rosen, Cornelis A. van Oeveren, Jason C. Pickens, Lin Zhi, Yixing Shen, Bijan Pedram
Filed: 6 Jan 20
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