10 patents
Utility
Amorphous solid succinylated 3-(fatty acid amido)-2-hydroxy-1 -(protected hydroxy)-propane salts and methods of making the same
20 Dec 22
Aspects of the disclosure includes methods for preparing an amorphous solid composition of a fatty acid metal salt.
Jennifer E. Albaneze-Walker
Filed: 23 Oct 20
Utility
Methods of polynucleotide preparation using multivalent cation salt compositions
13 Sep 22
Aspects of the disclosure include methods for the preparation of a polynucleotide.
Premchandran H. Ramiya
Filed: 10 Jul 20
Utility
Process for preparing imetelstat
17 May 22
Jale Muslehiddinoglu, Dinesh Gala, Jennifer Elizabeth Albaneze-Walker
Filed: 9 Jul 18
Utility
Combination treatment for hematological cancers
22 Mar 22
The present invention relates to a combination treatment for hematological cancers.
Fei Huang, Joshua J. Rusbuldt, Aleksandra Rizo
Filed: 28 Jul 17
Utility
Guanine analogs as telomerase substrates and telomere length affectors
22 Mar 22
This invention relates to compounds useful for inhibiting telomere elongation.
Sergei M. Gryaznov, Ronald A. Pruzan, Krisztina Pongracz
Filed: 7 Feb 20
Utility
Methods of polynucleotide preparation using multivalent cation salt compositions
17 Aug 20
Aspects of the disclosure include methods for the preparation of a polynucleotide.
Premchandran H. Ramiya
Filed: 20 Apr 16
Utility
Synthesis of protected 3′-amino nucleoside monomers
10 Aug 20
Orthogonally protected 3′-amino nucleoside monomers and efficient methods for their synthesis are described.
Sergei M. Gryaznov, Krisztina Pongracz, Daria Zielinska
Filed: 28 Jun 18
Utility
RNA amidates and thioamidates for RNAi
18 May 20
The present disclosure relates to RNA amidates and thioamidates useful for RNA interference applications.
Sergei Gryaznov, Krisztina Pongracz
Filed: 17 Oct 17
Utility
Guanine analogs as telomerase substrates and telomere length affectors
17 Feb 20
This invention relates to compounds useful for inhibiting telomere elongation.
Sergei M. Gryaznov, Ronald A. Pruzan, Krisztina Pongracz
Filed: 21 Jun 18
Utility
Phosphorodiamidate backbone linkage for oligonucleotides
2 Dec 19
This invention relates to antisense oligonucleotides comprising at least one N3′→P5′ phosphorodiamidate linkage (NPN) in the backbone, useful for modulating gene expression involved in the pathogenesis of a disease.
Krisztina Pongracz, Mahesh Ramaseshan
Filed: 6 Jun 17
- Prev
- 1
- Next
Patents are sorted by USPTO publication date, most recent first