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AMRN Amarin

GRANT
Utility
Compositions and methods for lowering levels of high-sensitivity C-reactive protein (hs-CRP) in a subject
13 Apr 21
The present disclosure provides methods for treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 24 Oct 17
GRANT
Utility
Methods of reducing apolipoprotein c-III
13 Apr 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Joseph S. Zakrzewski
Filed: 27 Feb 20
APP
Utility
Methods of Treating Mixed Dyslipidemia
8 Apr 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 18 Dec 20
APP
Utility
Methods of Treating Mixed Dyslipidemia
8 Apr 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 18 Dec 20
APP
Utility
Methods of Reducing the Risk of Cardiovascular Events In a Subject
8 Apr 21
In various embodiments, the present disclosure provides methods reducing the risk of cardiovascular events in a subject on statin therapy by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 18 Dec 20
GRANT
Utility
Compositions and methods for lowering triglycerides in a subject having reduced kidney function
6 Apr 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject having reduced kidney function.
Sephy Philip
Filed: 18 May 18
GRANT
Utility
Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
6 Apr 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing triglycerides in a subject on rosiglitazone therapy, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Rene Braeckman, William Stirtan, Paresh Soni
Filed: 6 Jun 14
APP
Utility
Methods of Reducing or Preventing Oxidation of Small Dense LDL or Membrane Polyunsaturated Fatty Acids
25 Mar 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing or preventing sdLDL oxidation in a subject, the method comprising administering to the subject a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Richard Preston Mason
Filed: 19 Oct 20
APP
Utility
Methods of Treating Hypertriglyceridemia
11 Mar 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 23 Nov 20
APP
Utility
Compositions and Methods for Reducing a Fatty Acid Desaturation Index In a Subject In Need Thereof
11 Mar 21
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Rene Braeckman, William Stirtan, Paresh Soni
Filed: 24 Aug 20
GRANT
Utility
Methods of treating mixed dyslipidemia
9 Mar 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 2 Nov 18
APP
Utility
Methods of Treating Hypertriglyceridemia
18 Feb 21
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 1 Sep 20
APP
Utility
Low Eructation Composition and Methods for Treating And/or Preventing Cardiovascular Disease In a Subject with Fish Allergy/hypersensitivity
18 Feb 21
In various embodiments, the present invention provides pharmaceutical compositions and methods for treating cardiovascular-related disease.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Jonathan Rowe
Filed: 3 Nov 20
GRANT
Utility
Methods of reducing the risk of a cardiovascular event in a subject at risk for cardiovascular disease
19 Jan 21
In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
Paresh Soni
Filed: 29 Jan 20
GRANT
Utility
Pharmaceutical compositions comprising omega-3 fatty acids
12 Jan 21
The present disclosure relates to, inter alia, pharmaceutical compositions comprising omega-3 fatty acids.
Mehar Manku, Jonathan Rowe
Filed: 7 Nov 14
GRANT
Utility
Methods of treating or preventing prostate cancer
12 Jan 21
In various embodiments, the present invention provides methods of treating and/or preventing prostate cancer and, in particular, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
Joseph S. Zakrzewski
Filed: 13 Sep 17
APP
Utility
Methods of Treating Mixed Dyslipidemia
6 Jan 21
The present disclosure relates to, inter alia, methods of treating mixed dyslipidemia with ethyl eicosapentaenoate.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 20 Sep 20
GRANT
Utility
Stable pharmaceutical composition and methods of using same
4 Jan 21
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 4 Jun 20
APP
Utility
Stable Pharmaceutical Composition and Methods of Using Same
30 Dec 20
The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
Mehar Manku, Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni
Filed: 9 Sep 20
APP
Utility
Compositions and Methods for Lowering Triglycerides Without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy
30 Dec 20
In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
Ian Osterloh, Pierre Wicker, Rene Braeckman, Paresh Soni, Mehar Manku
Filed: 9 Jun 20
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